Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

202673

Sigma-Aldrich

Arsenic(III) oxide

99.995% trace metals basis

Synonym(s):

ATO, Diarsenic trioxide;, Arsenic trioxide, Arsenous acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
As2O3
CAS Number:
1327-53-3
Molecular Weight:
197.84
EC Number:
215-481-4
MDL number:
MFCD00003433
UNSPSC Code:
12161600
eCl@ss:
38080102
PubChem Substance ID:
24852110
NACRES:
NA.22

Quality Level

200

Assay

99.995% trace metals basis

form

powder

reaction suitability

core: arsenic
reagent type: catalyst

SMILES string

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI key

IKWTVSLWAPBBKU-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Arsenic(III) oxide (ATO) is an inorganic form of arsenic that is used as a therapeutic compound for treating patients with acute promyelocytic leukemia (APL). Many drug-delivery methods are currently being developed using nanotechnology to overcome its poor bioavailability due to rapid clearance from blood.

Application


  • Electrochemical detection applications: A study on La-based perovskites incorporated with functionalized carbon nanofibers highlights the use of arsenic trioxide for the electrochemical detection of roxarsone in water and food samples, providing a method to improve safety and environmental monitoring (John Felix MA et al., 2024).

  • Antiproliferative effects in cancer research: Research demonstrates the inhibitory effects of arsenic trioxide, combined with metformin, on KG1a cell proliferation, suggesting its potential utility in developing antineoplastic strategies (Huang-Li WH et al., 2024).

  • Environmental remediation: A review on manganese oxide-based materials for arsenic removal discusses the application of arsenic trioxide in environmental remediation, focusing on the effectiveness and advancements in arsenic decontamination technologies (Younas M et al., 2024).

Signal Word

Danger

Hazard Statements

H300,H314,H350,H372,H410

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Target Organs

Respiratory system,Cardio-vascular system,Gastrointestinal tract

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A facile route to core?shell nanoparticulate formation of arsenic trioxide for effective solid tumor treatment.
Zhang Z, et al.
Nanoscale, 8(7), 4373-4380 (2016)
Recent advances in arsenic trioxide encapsulated nanoparticles as drug delivery agents to solid cancers.
Akhtar A, et al.
Journal of biomedical research, 31(3), 177-177 (2017)
Silica nanovehicles endow arsenic trioxide with an ability to effectively treat cancer cells and solid tumors.
Zhao Z, et al.
Journal of Materials Chemistry, 2(37), 6313-6323 (2014)
Ruoshi Xu et al.
Bone research, 6, 33-33 (2018-11-28)
How osteoblast cells are induced is a central question for understanding skeletal formation. Abnormal osteoblast differentiation leads to a broad range of devastating craniofacial diseases. Here we have investigated intramembranous ossification during cranial bone development in mouse models of skeletal
Yanfei Jia et al.
PloS one, 8(1), e54774-e54774 (2013-02-06)
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As(2)O(3)) is used clinically to treat acute promyelocytic leukemia(APL) and has
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service