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Merck
CN

202320

Poly(propylene glycol)

average Mn ~1,000

Synonym(s):

PPG, Poly(propylene oxide)

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About This Item

Linear Formula:
H[OCH(CH3)CH2]nOH
CAS Number:
25322-69-4
NACRES:
NA.23
PubChem Substance ID:
24852055
UNSPSC Code:
12162002
MDL number:
MFCD00084446
Vapor pressure:
<0.01 mmHg ( 20 °C)

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Product Name

Poly(propylene glycol), average Mn ~1,000

InChI

1S/C6H14O3/c1-5(8)4-9-6(2)3-7/h5-8H,3-4H2,1-2H3

SMILES string

CC(O)CO

InChI key

DUFKCOQISQKSAV-UHFFFAOYSA-N

vapor density

>1 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

mol wt

average Mn ~1,000

contains

130-190 ppm proprietary phenolic antioxidant

refractive index

n20/D 1.449

viscosity

150 cSt(25 °C)(lit.)

hydroxyl value

111 mg KOH/g

solubility

water: miscible (completely)

density

1.005 g/mL at 25 °C

Quality Level

200

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Application

Poly(propylene glycol) can be used:
  • As a precursor to synthesize multiblock thermo-responsive smart polymers for various biomedical applications. The presence of PPG is the main reason for the thermosensitivity of these polymers. For example, it can be used to synthesize poly(ester urethane)s.
  • For the surface modification of sisal fiber to enhance nucleating ability.

General description

Poly(propylene glycol) (PPG) is a biocompatible polymer widely used as a precursor to fabricate biomedical materials. It is soluble in water at low temperatures and becomes insoluble at high temperatures.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

445.0 °F - closed cup

flash_point_c

229.44 °C - closed cup

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX8800
MKCV1784
MKCQ0095
MKCK3351
MKBJ5298V

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Chang-Chin Wu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(8), 2232-2243 (2016-07-23)
Despite its common usage in vertebral augmentation procedures (VAPs), shortcomings of commercial polymethylmethacrylate (PMMA) still remain. Accordingly, injectable and biodegradable composite cements, which are composed of poly(propylene fumarate)/α-tricalcium/hydroxyapatite (PPF/α-TCP/HAP) and PPF/tetracalcium phosphate/dicalcium phosphate (PPF/TtCP/DCP), were developed. A porcine model was
John Texter et al.
Macromolecular rapid communications, 33(1), 69-74 (2011-12-03)
The controlled atom transfer radical polymerization of an ionic liquid, 1-(11-acryloylundecyl)-3-methyl imidazolium bromide (ILBr), from both ends of a telechelic poly(propylene oxide) (PPO) macroinitiator, end-functionalized with bromoisobutyryloyl is reported. The resulting highly water-soluble triblock, poly(ILBr-b-PO-b-ILBr) is multistimuli responsive. This new
Celeste R Brennecka et al.
World neurosurgery, 78(5), 469-480 (2011-11-29)
Current treatments for cerebral aneurysms are far from ideal. Platinum coils are prone to compaction, and currently used liquid embolics are delivered with angiotoxic agents. This work presents initial in vivo studies of a novel liquid-to-solid gelling polymer system (PPODA-QT)
Flávia Chiva Carvalho et al.
Journal of biomedical nanotechnology, 8(2), 280-289 (2012-04-21)
In the last few decades, nanotechnology has led to an advance in the development of topical drug delivery. Nanostructured drug delivery systems enable the compartmentalization of drugs in restricted environments, modifying the release profile and maintaining the required drug concentration
Mohammed Taghi Zafarani-Moattar et al.
Biotechnology progress, 28(1), 146-156 (2011-09-29)
In this work, we proposed a novel aqueous biphasic system (ABS) composed of polypropylene glycol P400 (PPG P400) and hydrophilic ionic liquids (IL), 1-alkyl-3-methylimidazolium bromide (alkyl = ethyl or butyl), forming an upper polymer-rich phase and a lower IL-rich phase
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