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200654

Sigma-Aldrich

Ethyl cellulose

viscosity 300 cP, 5 % in toluene/ethanol 80:20(lit.), extent of labeling: 48% ethoxyl

Synonym(s):

Ethylcellulose

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

form

granular

Quality Level

autoignition temp.

698 °F

concentration

48.0-49.5%

extent of labeling

48% ethoxyl

refractive index

n20/D 1.47 (lit.)

viscosity

300 cP, 5 % in toluene/ethanol 80:20(lit.)

transition temp

softening point 157 °C

density

1.14 g/mL at 25 °C (lit.)

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General description

Ethyl cellulose (EC) is a non-toxic, biocompatible, and hydrophobic polymer used for the sustained release preparation of pharmaceutical products.

Application

Ethyl cellulose can be used to prepare polymer coatings for various applications. For example, it is used to encapsulate salt hydrates for low-temperature heat storage applications.

It can be used as an efficient carrier for multiparticulate sustained drug delivery. For example, it can be used to develop polymeric microspheres for the controlled release of Ivabradine HCL (IBH).

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Dace Gao et al.
Nanoscale horizons, 5(4), 730-738 (2020-02-18)
The design and construction of 3D architectures enabled by stimuli-responsive soft materials can yield novel functionalities for next generation soft-bodied actuating devices. Apart from additive manufacturing processes, origami inspired technology offers an alternative approach to fabricate 3D actuators from planar
Kifayat Ullah Shah et al.
TheScientificWorldJournal, 2012, 842348-842348 (2012-06-01)
The design and fabrication of sustained/controlled release dosage forms, employing new excipients capable of extending/controlling the release of drugs from the dosage forms over prolonged periods, has worked well in achieving optimally enhanced therapeutic levels of the drugs. In this
Tetsuya Ozeki et al.
Biological & pharmaceutical bulletin, 35(11), 1926-1931 (2012-11-06)
Production of drug nanoparticles is an effective strategy to enhance solubility and oral absorption of water-insoluble drugs. The handling of drug nanoparticles has been an important issue in drug formulation because nanoparticles easily aggregate each other and redispersion of these
Oguzhan Gunduz et al.
Pharmaceutical research, 30(1), 225-237 (2012-09-08)
To investigate a new microfluidic method for the continuous preparation of hollow-shell nanoparticles of a hydrophobic polymer and the simultaneous encapsulation within these of a hydrophilic active pharmaceutical ingredient. A specially designed and constructed microfluidic device which facilitates at a
Ghulam Murtaza
Acta poloniae pharmaceutica, 69(1), 11-22 (2012-05-12)
Ethylcellulose (EC) based microencapsulated drug delivery systems are being extensively studied throughout the world for achieving extended drug release and protecting the core substance from degradation. The in vitro evaluation of EC microcapsules have elucidated that their particle characteristics are

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