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About This Item
Linear Formula:
H2NCH2CH2COCH2NH2 · 2HCl
CAS Number:
Molecular Weight:
175.06
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
222-914-0
MDL number:
Assay:
99%
InChI key
HDRKYQXFDHZZOW-UHFFFAOYSA-N
InChI
1S/C4H10N2O.2ClH/c5-2-1-4(7)3-6;;/h1-3,5-6H2;2*1H
SMILES string
Cl[H].Cl[H].NCCC(=O)CN
assay
99%
mp
221 °C (dec.) (lit.)
functional group
amine, ketone
Application
1,4-Diamino-2-butanone dihydrochloride was used as a media supplement for the growth of B.pertussis and B. bronchiseptica.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Georgina E Reyna-López et al.
Current microbiology, 48(2), 118-123 (2004-04-02)
We utilized our modification of the amplified fragment length polymorphism technique for the determination of changes occurring in the DNA methylation patterns during the dimorphic transition of the fungi Mucor rouxii, Yarrowia lipolytica, and Ustilago maydis. To determine the specificity
C Maia et al.
Parasitology research, 103(2), 363-370 (2008-04-26)
The protozoan Giardia lamblia is the most frequent intestinal parasite of first-world countries and a major cause of waterborne disorder often referred to as traveler's diarrhea. We have previously noticed that the putrescine analog 1,4-diamino-2-butanone (DAB) remarkably inhibits the growth
Marcos A Vannier-Santos et al.
Microbiology (Reading, England), 154(Pt 10), 3104-3111 (2008-10-04)
Polyamines are important regulators of growth and differentiation in a variety of cells, including parasitic protozoa. Promastigotes of Leishmania species have high levels of putrescine and spermidine and their growth can be inhibited by polyamine biosynthesis antagonists. The putrescine analogue
C Cano et al.
Journal of bacteriology, 170(12), 5946-5948 (1988-12-01)
DNA from intact or spherically growing spores of Mucor rouxii is highly methylated, whereas DNA from germlings has low levels of methylation. DNA from spores incubated with hydroxyurea or 1,4-diaminobutanone is also highly methylated. The reversal of the effect of
A G Tkachenko et al.
Mikrobiologiia, 70(4), 487-494 (2001-09-18)
The level of expression of oxyR, the gene that protects Escherichia coli against oxidative stress, was enhanced by physiological concentrations of the biogenic amine putrescine. This level was directly proportional to the degree of negative DNA supercoiling. 1,4-Diamino-2-butanone (DAB), a
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