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197777

Sigma-Aldrich

2-(p-Chlorophenoxy)-2-methylpropionic acid

97%

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Synonym(s):
α-(p-Chlorophenoxy)isobutyric acid, Clofibric acid
Linear Formula:
ClC6H4OC(CH3)2CO2H
CAS Number:
882-09-7
Molecular Weight:
214.65
EC Number:
212-925-9
MDL number:
MFCD00004192
UNSPSC Code:
12352100
PubChem Substance ID:
24851846
NACRES:
NA.22

Quality Level

200

Assay

97%

mp

120-122 °C (lit.)

SMILES string

CC(C)(Oc1ccc(Cl)cc1)C(O)=O

InChI

1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)

InChI key

TXCGAZHTZHNUAI-UHFFFAOYSA-N

Gene Information

human ... PPARA(5465) , PPARG(5468)
mouse ... Ppara(19013) , Pparg(19016)

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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R Salgado et al.
Journal of hazardous materials, 241-242, 182-189 (2012-10-16)
Clofibric acid (CLF) is the pharmaceutically active metabolite of lipid regulators clofibrate, etofibrate and etofyllinclofibrate, and it is considered both environmentally persistent and refractory. This work studied the biotransformation of CLF in aerobic sequencing batch reactors (SBRs) with mixed microbial
Chao-meng Dai et al.
Environmental science and pollution research international, 20(8), 5492-5501 (2013-02-26)
A novel double templates-molecularly imprinted polymer (MIP) was prepared by precipitation polymerization using carbamazepine (CBZ) and clofibric acid (CA) as the double templates molecular and 2-vinylpyridine as functional monomer. The equilibrium data of MIP was well described by the Freundlich
Julia Martín et al.
Journal of environmental management, 102, 18-25 (2012-03-20)
In this work, the distribution and the ecotoxicological risk of sixteen pharmaceutically active compounds belonging to seven different therapeutic groups (five anti-inflammatory drugs, two antibiotics, an anti-epileptic drug, a β-blocker, a nervous stimulant, four estrogens and two lipid regulators) have
Dong Qing Zhang et al.
Environmental pollution (Barking, Essex : 1987), 167, 124-131 (2012-05-09)
This study evaluated the effect of continuous and batch feeding on the removal of 8 pharmaceuticals (carbamazepine, naproxen, diclofenac, ibuprofen, caffeine, salicylic acid, ketoprofen and clofibric acid) from synthetic wastewater in mesocosm-scale constructed wetlands (CWs). Both loading modes were operated
Uwe Kunkel et al.
Environmental science & technology, 45(15), 6296-6302 (2011-06-16)
The fate of pharmaceutically active substances in rivers is still only incompletely understood, especially as the knowledge transfer from laboratory experiments to the real world is complicated by factors like turbidity, hydrodynamics, or heterogeneity. Therefore, we performed a tracer test
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