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Assay
96%
form
liquid
refractive index
n20/D 1.471 (lit.)
bp
85-88 °C/12 mmHg (lit.)
density
1.279 g/mL at 25 °C (lit.)
storage temp.
2-8°C
SMILES string
CCOC(=O)C1(Br)CCC1
InChI
1S/C7H11BrO2/c1-2-10-6(9)7(8)4-3-5-7/h2-5H2,1H3
InChI key
UTVNSHXHFRIXMM-UHFFFAOYSA-N
Application
Ethyl 1-bromocyclobutanecarboxylate was used in the synthesis of 1−aminocyclobutane carboxylic acid.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
WGK
WGK 3
Flash Point(F)
174.2 °F
Flash Point(C)
79 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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An Efficient Procedure for Preparation of C−and N−Protected 1−Aminocyclobutane Carboxylic Acid.
Synthetic Communications, 34(4), 607-613 (2004)
Molecules (Basel, Switzerland), 25(18) (2020-09-19)
Glucocorticoid metabolism at the tissue level is regulated by two isoenzymes 11β-hydroxysteroid dehydrogenase (11β-HSD), which mutually convert biologically active cortisol and inactive cortisone. Recent research is focused on the role of 11β-HSD1 and 11β-HSD2 as autocrine factors of tumor cell
Chemistry & biodiversity, 16(6), e1900065-e1900065 (2019-04-24)
11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) is an enzyme that affects the body's cortisol levels. The inhibition of its activity can be used in the treatment of Cushing's syndrome, metabolic syndrome and type 2 diabetes. In this study, we synthesized new
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