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About This Item
Linear Formula:
(CH3)3CNHOH · HCl
CAS Number:
Molecular Weight:
125.60
Beilstein:
3546053
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥98%
form
solid
mp
183-185 °C (lit.)
SMILES string
Cl.CC(C)(C)NO
InChI
1S/C4H11NO.ClH/c1-4(2,3)5-6;/h5-6H,1-3H3;1H
InChI key
DCSATTBHEMKGIP-UHFFFAOYSA-N
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Application
N-tert-Butylhydroxylamine hydrochloride was used in spin trapping of short-lived radicals. It was also used in the synthesis of α-ketoamides and 3-spirocyclopropanated 2-azetidinones.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Hyun Jeong Kim et al.
Redox report : communications in free radical research, 10(6), 287-293 (2006-01-28)
Heat shock may increase oxidative stress due to increased production of reactive oxygen species and/or the promotion of cellular oxidation events. Therefore, compounds that scavenge reactive oxygen species may regulate heat shock-induced cell death. Recently, it has been shown that
Yu-Kyung Kim et al.
Clinical hemorheology and microcirculation, 40(4), 315-324 (2009-01-08)
Irradiation has been shown to induce biochemical changes in stored red blood cells (RBCs) and to generate reactive oxygen species (ROS). This study evaluated the hemorheological properties, the degree of lipid peroxidation and the oxidative susceptibility of irradiated RBCs. Furthermore
David W Killilea et al.
Annals of the New York Academy of Sciences, 1019, 365-367 (2004-07-13)
Iron accumulates as a function of age and is associated with the pathology of numerous age-related diseases. These changes may be caused by altered iron homeostasis at the cellular level, yet this is poorly understood. Therefore, changes in iron content
Synthesis of alpha-ketoamides by a molecular-sieves-promoted formal oxidative coupling of aliphatic aldehydes with isocyanides.
Jean-Marie Grassot et al.
Angewandte Chemie (International ed. in English), 47(5), 947-950 (2007-12-20)
C Lagercrantz
Free radical research communications, 14(5-6), 395-407 (1991-01-01)
Spin trapping of short-lived R. radicals is done by use of N-tert-butylhydroxylamine (1) and H2O2. The hydroxylamine is oxidized to the radical t-BuN(O)H (2) which is converted into the spin trap 2-methyl-2-nitrosopropane (3). Simultaneously, hydroxyl radicals .OH are formed from
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