192279
1-Amino-1-cyclopentanemethanol
97%
Synonym(s):
Cycloleucinol
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About This Item
Linear Formula:
H2NC5H8CH2OH
CAS Number:
Molecular Weight:
115.17
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
233-697-7
MDL number:
Assay:
97%
InChI key
PDNZJLMPXLQDPL-UHFFFAOYSA-N
InChI
1S/C6H13NO/c7-6(5-8)3-1-2-4-6/h8H,1-5,7H2
SMILES string
NC1(CO)CCCC1
assay
97%
bp
85-90 °C/10 mmHg (lit.)
mp
20 °C (lit.)
functional group
hydroxyl
Application
1-Amino-1-cyclopentanemethanol was used in the synthesis of xanthine-derived heterocyclic fused systems. It was also used as building block in medicinal chemistry synthesis.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
204.8 °F - closed cup
flash_point_c
96 °C - closed cup
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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David C Pryde et al.
Journal of medicinal chemistry, 49(14), 4409-4424 (2006-07-11)
Female sexual arousal disorder (FSAD) is a highly prevalent sexual disorder affecting up to 40% of women. We describe herein our efforts to identify a selective neutral endopeptidase (NEP) inhibitor as a potential treatment for FSAD. The rationale for this
Methods for the synthesis of xanthine-derived polycyclic fused systems.
Szymanska E, et al.
Heterocyclic Communications, 19(5), 297-310 (2013)
Paul V Fish et al.
Journal of medicinal chemistry, 50(10), 2341-2351 (2007-04-24)
1-isoquinolinylguanidines were previously disclosed as potent and selective inhibitors of urokinase-type plasminogen activator (uPA). Further investigation of this template has revealed that incorporation of a 7-sulfonamide group furnishes a new series of potent and highly selective uPA inhibitors. Potency and
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