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Quality Level
Assay
99%
form
liquid
refractive index
n20/D 1.560 (lit.)
bp
142-143 °C/21 mmHg (lit.)
mp
15-17 °C
density
1.462 g/mL at 25 °C (lit.)
SMILES string
ClC(=O)c1c(Cl)cccc1Cl
InChI
1S/C7H3Cl3O/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H
InChI key
JBLIDPPHFGWTKU-UHFFFAOYSA-N
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General description
2,6-Dichlorobenzoyl chloride participates in esterification of (fluoren-9-ylmethoxy)carbonyl (Fmoc)-amino acids to 4-alkoxybenzyl alcohol polystyrene.
Application
2,6-Dichlorobenzoyl chloride was used:
- in substrate activity screening method for the rapid development of novel substrates and their conversion into non-peptidic inhibitors of Cys and Ser proteases
- in the synthesis of 1-acyliridoles
- in enantiocontrolled total synthesis of (-)-aspicilin
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
WGK
WGK 1
Flash Point(F)
closed cup
Flash Point(C)
closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Morphine recognition by a porphyrin-cyclocholate molecular bowl.
Journal of the Chemical Society. Chemical Communications, 5, 456-458 (1993)
An improved method for anchoring of 9-fluorenylmethoxycarbonyl-amino acids to 4-alkoxybenzyl alcohol resins.
Tetrahedron Letters, 28(49), 6147-6150 (1987)
Sensitisation to dichlorobenzoyl chloride.
Contact dermatitis, 18(2), 116-117 (1988-02-01)
Stereocontrolled total synthesis of the macrocyclic lactone (-)-aspicilin.
Tetrahedron Letters, 28(21), 2409-2412 (1987)
Nature protocols, 2(2), 424-433 (2007-04-05)
Substrate activity screening (SAS) is a fragment-based method for the rapid development of novel substrates and their conversion into non-peptidic inhibitors of Cys and Ser proteases. The method consists of three steps: (i) a library of N-acyl aminocoumarins with diverse
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