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185213

Sigma-Aldrich

1,1,4,4-Tetraphenyl-1,3-butadiene

suitable for scintillation, ≥99%

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Synonym(s):
TPB
Linear Formula:
(C6H5)2C=CHCH=C(C6H5)2
CAS Number:
Molecular Weight:
358.47
Beilstein:
1914229
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

Quality Level

Assay

≥99%

form

solid

mp

207-209 °C (lit.)

suitability

suitable for scintillation

SMILES string

c1ccc(cc1)\C(=C\C=C(/c2ccccc2)c3ccccc3)c4ccccc4

InChI

1S/C28H22/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)21-22-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26/h1-22H

InChI key

KLCLIOISYBHYDZ-UHFFFAOYSA-N

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Application


  • Antihistamine biochemical reagent: Diphenhydramine hydrochloride is widely used as a potent H1 histamine receptor antagonist in biochemical assays to study allergic reactions and antihistamine effects, underscoring its utility in pharmacological research (Quinn et al., 2024).

  • In vitro pharmacological studies: This compound serves as a critical tool in in vitro pharmacological studies, particularly for understanding the dynamics of histamine interactions and receptor activity, providing essential insights into allergic response mechanisms (Pitts et al., 2024).

  • Diphenhydramine hydrochloride solubility: Its solubility in various solvents makes it an ideal candidate for experiments requiring precise dosages and concentrations in solution form, facilitating its use in liquid pharmaceutical formulations and research applications (Kumar et al., 2023).

  • High purity Diphenhydramine HCl for biochemical research: The availability of high-purity diphenhydramine hydrochloride is crucial for conducting accurate and reproducible research, especially in studies related to its pharmacokinetics and pharmacodynamics (Pitts et al., 2024).

  • Diphenhydramine HCl aqueous solution for scientific laboratory use: This compound is often prepared in aqueous solutions for experimental use, supporting various scientific studies that require a well-characterized antagonist to explore the pathways and effects of histamine in biological systems (Kumar et al., 2023).

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Suzuki, H., Izumi, T., Yamamoto, H., Tao, X. T., Watanabe, T., Usui, H., & Miyata, S.
Journal of Applied Physics, 88(10), 5791-5795 (2000)
Determination of the absolute quantum efficiency of luminescence of solid materials employing photoacoustic spectroscopy
Adams, M. J., Highfield, J. G., & Kirkbright, G. F.
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Journal of the American Chemical Society, 97(11), 2978-2985 (1975)
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