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Key Documents

Safety Information

183784

Sigma-Aldrich

4-Chlorosalicylic acid

93%

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About This Item

Linear Formula:
ClC6H3(OH)CO2H
CAS Number:
Molecular Weight:
172.57
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

93%

form

solid

mp

210-212 °C (lit.)

functional group

carboxylic acid
chloro

SMILES string

OC(=O)c1ccc(Cl)cc1O

InChI

1S/C7H5ClO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,(H,10,11)

InChI key

LWXFCZXRFBUOOR-UHFFFAOYSA-N

Application

4-Chlorosalicylic acid was used in sensitive spectrofluorometric determination of terbium in mixed rare earths. It was used in preparation of poly(4-chlorosalicylic acid-formaldehyde) via condensation with formaldehyde.

Biochem/physiol Actions

4-Chlorosalicylic acid shows potent antibacterial activity against Escherichia coli.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Inhibitory effects of 4-chlorosalicylic acid on mushroom tyrosinase and its antimicrobial activities.
Han P, et al.
Food Chemistry, 107(2), 797-803 (2008)
4-Chlorosalicylic acid-formaldehyde polymer as a polymeric ligand.
Patel HS, et al.
Makromol. Chem., 106(1), 223-237 (1982)
Wei Jiang et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 19(6), 923-925 (2003-07-02)
The quadruple complex formed by terbium with 4-chlorosalicylic acid (CSA), EDTA and cetyltrimethylammonium bromide (CTMAB) has been used for the sensitive spectrofluorometric determination of terbium in mixed rare earths. The effect of the experimental conditions on the fluorescence intensity was
Sonja Pawelczyk et al.
Journal of microbiological methods, 75(1), 117-126 (2008-07-03)
4-Chlorosalicylate (4-CS) can be degraded completely by a bacterial consortium consisting of Pseudomonas reinekei (MT1), Achromobacter spanius (MT3) and Pseudomonas veronii (MT4). The fourth species Wautersiella falsenii (MT2) is thought to act as a 'necrotizer' of the community. Single cell
Roberto A Bobadilla Fazzini et al.
Proteomics, 9(8), 2273-2285 (2009-04-22)
In this study, the stable consortium composed by Pseudomonas reinekei strain MT1 and Achromobacter xylosoxidans strain MT3 (cell numbers in proportion 9:1) was under investigation to reveal bacterial interactions that take place under severe nutrient-limiting conditions. The analysis of steady

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