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Merck
CN

180629

Diphenyl diselenide

98%

Synonym(s):

Phenyl diselenide

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About This Item

Linear Formula:
C6H5SeSeC6H5
CAS Number:
Molecular Weight:
312.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
216-780-2
Beilstein/REAXYS Number:
2047179
MDL number:
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Product Name

Diphenyl diselenide, 98%

assay

98%

InChI key

YWWZCHLUQSHMCL-UHFFFAOYSA-N

InChI

1S/C12H10Se2/c1-3-7-11(8-4-1)13-14-12-9-5-2-6-10-12/h1-10H

SMILES string

[Se]([Se]c1ccccc1)c2ccccc2

impurities

<2% diphenyl selenide

mp

59-61 °C (lit.)

Quality Level

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Application

Diphenyl diselenide is used:In the synthesis of diaryl selenides bycross-coupling of aryl halides with diphenyl diselenide in presence of copperferrite nanoparticle catalyst.

Biochem/physiol Actions

Diphenyl diselenide inhibits δ-aminolevulinate dehydratase (δ-ALA-D) from brain, liver and kidney in vitro.

General description

Diphenyl Diselenide is an organo selenium compound that is an oxidized derivative of benzeneselenol. It is a source of phenylseleno radicals. it is reactive with a wide range of organic nucleophiles, electrophiles, and radicals.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

危险化学品
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E N Maciel et al.
Journal of biochemical and molecular toxicology, 14(6), 310-319 (2000-11-18)
In the present study, the inhibitory effect of diphenyl diselenide and diphenyl ditelluride after in vitro, acute (a single dose), or chronic exposure (14 doses) was examined in mice 24 hours after the last administration. In vitro, diphenyl diselenide, and
Diphenyl Diselenide-Catalyzed Synthesis of Triaryl Phosphites and Triaryl Phosphates from White Phosphorus
Zhang Y, et al.
Organic Letters, 23(13), 5158-5163 (2021)
Diphenyl Diselenide
Byers JH
Encyclopedia of Reagents for Organic Synthesis, Second Edition (2001)
César A Brüning et al.
Neurochemical research, 37(10), 2249-2258 (2012-08-01)
Cerebrovascular diseases, including ischemic stroke, are associated with high mortality worldwide. Oxidative stress and inflammation are important pathophysiological mechanisms involved in post-ischemic cerebral injury. The present study was designed to investigate the potential protective effect of diphenyl diselenide (PhSe)(2), an
Juliana T da Rocha et al.
Behavioural pharmacology, 23(1), 98-104 (2011-12-06)
Ovarian hormone loss contributes to cognitive decline in postmenopausal women. Studies have demonstrated a positive role of the level of the element selenium in cognitive performance. The present study investigated the effects of the synthetic organoselenium compound diphenyl diselenide (PhSe)₂

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