17988
DL-β-Leucine
≥98.0% (NT)
Synonym(s):
(±)-3-Amino-4-methylpentanoic acid, (±)-3-Amino-4-methylvaleric acid
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About This Item
Empirical Formula (Hill Notation):
C6H13NO2
CAS Number:
Molecular Weight:
131.17
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
1747371
MDL number:
Product Name
DL-β-Leucine, ≥98.0% (NT)
SMILES string
CC(C)C(N)CC(O)=O
InChI
1S/C6H13NO2/c1-4(2)5(7)3-6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)
InChI key
GLUJNGJDHCTUJY-UHFFFAOYSA-N
assay
≥98.0% (NT)
application(s)
peptide synthesis
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J M Poston
The Journal of biological chemistry, 255(21), 10067-10072 (1980-11-10)
Circulating levels of beta-leucine are elevated in the cobalamin-deficient state of pernicious anemia. Levels of leucine, on the other hand, are much lower. It is proposed that leucine 2,3-aminomutase, the cobalamin-dependent enzyme that catalyzes the interconversion of leucine and beta-leucine
Evaristo Peggion et al.
Biochemistry, 41(25), 8162-8175 (2002-06-19)
The 1-34 N-terminal fragments of human parathyroid hormone (PTH) and PTH-related protein (PTHrP) elicit the full spectrum of bone-relevant activities characteristic of the intact hormones. The structural elements believed to be required for receptor binding and biological activity are two
Cobalamin-dependent leucine and beta-leucine synthesis in higher animals.
Nutrition reviews, 39(6), 244-246 (1981-06-01)
Beta-amino acids: mammalian metabolism and utility as alpha-amino acid analogues.
O W Griffith
Annual review of biochemistry, 55, 855-878 (1986-01-01)
P E Coffey et al.
Chemical communications (Cambridge, England), (22)(22), 2330-2331 (2002-09-21)
Poly-beta-leucines have been evaluated as catalysts for the Juliá-Colonna asymmetric epoxidation of enones; the beta 3-isomer was found to be an effective catalyst for the epoxidation of chalcone (70% ee) and some analogues.
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