177377
Diphenylcyclopropenone
98%
Synonym(s):
DPC
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About This Item
Empirical Formula (Hill Notation):
C15H10O
CAS Number:
Molecular Weight:
206.24
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-948-4
Beilstein/REAXYS Number:
608049
MDL number:
Assay:
98%
InChI key
HCIBTBXNLVOFER-UHFFFAOYSA-N
InChI
1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H
SMILES string
O=C1C(c2ccccc2)=C1c3ccccc3
assay
98%
Quality Level
mp
118-122 °C (lit.)
functional group
ketone, phenyl
Related Categories
General description
Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.
Application
Diphenylcyclopropenone was used in topical immunotherapy.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Valerio Tabacchini et al.
Physics in medicine and biology, 60(14), 5513-5525 (2015-07-03)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the
Leena M Koulu et al.
The Journal of investigative dermatology, 130(11), 2578-2582 (2010-07-09)
Polymorphic light eruption (PLE) is a common skin disorder provoked by exposure to UVR. Its clinical symptoms resemble those of a contact allergic reaction. PLE is generally considered a T-cell-mediated autoimmune reaction toward a yet unidentified antigen formed in UVR-exposed
Frank Martiniuk et al.
Journal of drugs in dermatology : JDD, 9(11), 1368-1372 (2010-11-11)
The authors provide an update on a previously reported patient with in-transit metastatic melanoma of the scalp treated with topical diphencyprone (DPCP). Molecular studies implicate the thymus-derived TH17 lymphocyte subset in a remarkable immunotherapeutic regression. The authors performed RT-PCR of
Jesper Dyrendom Svalgaard et al.
Immunologic research, 58(1), 40-50 (2014-01-05)
p-Phenylenediamine (PPD) and Diphenylcyclopropenone (DPCP) are two potent haptens. Both haptens are known to cause delayed-type hypersensitivity, involving a cytokine response and local infiltration of T-cell subpopulations, resulting in contact dermatitis. We investigated the systemic immune effects of PPD and
Abdullah Alkhalifah et al.
Journal of the American Academy of Dermatology, 62(2), 191-202 (2010-02-02)
Various therapeutic agents have been described for the treatment of alopecia areata (AA), but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. The high rate of spontaneous remission and the
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