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Sigma-Aldrich

Diphenylcyclopropenone

98%

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Synonym(s):
DPC
Empirical Formula (Hill Notation):
C15H10O
CAS Number:
Molecular Weight:
206.24
Beilstein:
608049
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

mp

118-122 °C (lit.)

SMILES string

O=C1C(c2ccccc2)=C1c3ccccc3

InChI

1S/C15H10O/c16-15-13(11-7-3-1-4-8-11)14(15)12-9-5-2-6-10-12/h1-10H

InChI key

HCIBTBXNLVOFER-UHFFFAOYSA-N

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General description

Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.

Application

Diphenylcyclopropenone was used in topical immunotherapy.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Skin Sens. 1

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Valerio Tabacchini et al.
Physics in medicine and biology, 60(14), 5513-5525 (2015-07-03)
Gamma-ray detectors based on bright monolithic scintillation crystals coupled to pixelated photodetectors are currently being considered for several applications in the medical imaging field. In a typical monolithic detector, both the light intensity and the time of arrival of the
Yunseok Choi et al.
Annals of dermatology, 25(4), 434-439 (2013-12-29)
There exists a treatment challenge with periungual warts. Topical immunotherapy with diphenylcyclopropenone (DPCP) has recently been reported to be an effective treatment for recalcitrant warts, including periungual types. We aimed to evaluate the effectiveness and preference of topical immunotherapy with
T Kjeld et al.
Scandinavian journal of medicine & science in sports, 25(3), e253-e257 (2014-08-22)
Free diving is associated with extreme hypoxia. This study evaluated the combined effect of maximal static breath holding and underwater swimming on plasma biomarkers of tissue hypoxemia: erythropoietin, neuron-specific enolase and S100B, C-reactive protein, pro-atrial natriuretic peptide, and troponin T.
Frank Martiniuk et al.
Journal of drugs in dermatology : JDD, 9(11), 1368-1372 (2010-11-11)
The authors provide an update on a previously reported patient with in-transit metastatic melanoma of the scalp treated with topical diphencyprone (DPCP). Molecular studies implicate the thymus-derived TH17 lymphocyte subset in a remarkable immunotherapeutic regression. The authors performed RT-PCR of
Abdullah Alkhalifah et al.
Journal of the American Academy of Dermatology, 62(2), 191-202 (2010-02-02)
Various therapeutic agents have been described for the treatment of alopecia areata (AA), but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. The high rate of spontaneous remission and the

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