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Sigma-Aldrich

Isopropyl myristate

98%

Synonym(s):

Isopropyl tetradecanoate, Myristic acid isopropyl ester

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About This Item

Linear Formula:
CH3(CH2)12COOCH(CH3)2
CAS Number:
110-27-0
Molecular Weight:
270.45
Beilstein:
1781127
EC Number:
203-751-4
MDL number:
MFCD00008982
UNSPSC Code:
12352100
eCl@ss:
39022421
PubChem Substance ID:
24850403
NACRES:
NA.22

Quality Level

100

Assay

98%

form

liquid

refractive index

n20/D 1.434 (lit.)

bp

193 °C/20 mmHg (lit.)

mp

~3 °C (lit.)

density

0.85 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCCCCCC(=O)OC(C)C

InChI

1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3

InChI key

AXISYYRBXTVTFY-UHFFFAOYSA-N

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General description

IPM is a fatty acid ester that can be produced by the esterification of isopropyl alcohol and myristic acid.

Application

Isopropyl myristate was used as oil phase in the preparation of formulations. It was also used as oil/water-type tacrolimus (FK506) solvent.

Storage Class Code

10 - Combustible liquids

WGK

awg

Flash Point(F)

>302.0 °F

Flash Point(C)

> 150 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Neslihan Ustündağ Okur et al.
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Naproxen (Np) is an example of a non-steroidal anti-inflammatory drug (NSAID) commonly used for the reduction of pain and inflammation. In order to develop an alternative formulation for the topical administration of Np, microemulsions were evaluated as delivery vehicles. Four
Green synthesis of isopropyl myristate in novel single phase medium Part I: Batch optimization studies
Vadgama R, et al.
Biotechnology reports (Amsterdam, Netherlands), 8, 133-137 (2015)
Masayuki Yamanaka et al.
International journal of pharmaceutics, 464(1-2), 19-26 (2014-01-25)
We developed an oil/water-type tacrolimus (FK506) cream formulation as an alternative to Protopic ointment for atopic dermatitis treatment. We determined the effects of solvents used in topical preparations on FK506 solubility and stability, and evaluated FK506 transdermal absorption into rat
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(47), 15669-15678 (2014-11-21)
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