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Sigma-Aldrich

4-(Trifluoromethyl)-L-phenylglycine

≥98.0%

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Synonym(s):
(S)-2-Amino-2-[4-(trifluoromethyl)phenyl]acetic acid
Empirical Formula (Hill Notation):
C9H8F3NO2
CAS Number:
144789-75-3
Molecular Weight:
219.16
MDL number:
MFCD00236329
UNSPSC Code:
12352209
PubChem Substance ID:
57647580
NACRES:
NA.22

Quality Level

100

Assay

≥98.0%

reaction suitability

reaction type: solution phase peptide synthesis

application(s)

peptide synthesis

SMILES string

N[C@H](C(O)=O)c1ccc(cc1)C(F)(F)F

InChI

1S/C9H8F3NO2/c10-9(11,12)6-3-1-5(2-4-6)7(13)8(14)15/h1-4,7H,13H2,(H,14,15)/t7-/m0/s1

InChI key

FANMQHUKZBBELZ-ZETCQYMHSA-N

Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Jingliang Zhang et al.
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Scn2a encodes the voltage-gated sodium channel NaV1.2, a main mediator of neuronal action potential firing. The current paradigm suggests that NaV1.2 gain-of-function variants enhance neuronal excitability, resulting in epilepsy, whereas NaV1.2 deficiency impairs neuronal excitability, contributing to autism. However, this

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