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164798

Sigma-Aldrich

Trifluoromethanesulfonyl chloride

≥99%

Synonym(s):

Triflyl chloride

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About This Item

Linear Formula:
CF3SO2Cl
CAS Number:
Molecular Weight:
168.52
Beilstein:
1812106
EC Number:
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.22

vapor pressure

10.36 psi ( 20 °C)

Quality Level

Assay

≥99%

form

liquid

refractive index

n20/D 1.334 (lit.)

bp

29-32 °C (lit.)

density

1.583 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

FC(F)(F)S(Cl)(=O)=O

InChI

1S/CClF3O2S/c2-8(6,7)1(3,4)5

InChI key

GRGCWBWNLSTIEN-UHFFFAOYSA-N

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Application

Trifluoromethanesulfonyl chloride can be used as:
  • A trifluoromethylating agent for the fluoroalkylation of heterocycles, arenes, and heteroarenes.
  • A sulfonating agent for alcohols.
  • A chlorinating agent for carbanions.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Supplementary Hazards

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of the Chemical Society. Perkin Transactions 1, 627-627 (1991)
Marleen Häring et al.
The Journal of organic chemistry, 83(15), 7928-7938 (2018-05-29)
In this work, we demonstrate that useful C-C bond-forming photoredox catalysis can be performed in air using easily prepared gel networks as reaction media to give similar results as are obtained under inert atmosphere conditions. These reactions are completely inhibited
Journal of the Chemical Society. Perkin Transactions 1, 1339-1339 (1994)

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