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Merck
CN

158259

O-Methyl-L-tyrosine

98%

Synonym(s):

4-Methoxy-L-phenylalanine

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About This Item

Linear Formula:
CH3OC6H4CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
195.22
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
EC Number:
228-333-9
Beilstein/REAXYS Number:
2212726
MDL number:
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InChI key

GEYBMYRBIABFTA-VIFPVBQESA-N

InChI

1S/C10H13NO3/c1-14-8-4-2-7(3-5-8)6-9(11)10(12)13/h2-5,9H,6,11H2,1H3,(H,12,13)/t9-/m0/s1

SMILES string

COc1ccc(C[C@H](N)C(O)=O)cc1

assay

98%

optical activity

[α]25/D −7°, c = 0.5 in 1 M HCl

reaction suitability

reaction type: solution phase peptide synthesis

mp

259-261 °C (dec.) (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Debbie Dewaele et al.
Rapid communications in mass spectrometry : RCM, 30(6), 719-730 (2016-02-13)
Melphalan is a frequently used chemotherapeutical agent for the treatment of myeloma, breast cancer, ovarian cancer and sarcoma of soft tissue. A good knowledge of the reactivity of the drug toward the different amino acids, e.g. covalent adduct formation, is
Ma Diarey Tianero et al.
Nature microbiology, 4(7), 1149-1159 (2019-04-03)
Marine sponges often house small-molecule-producing symbionts extracellularly in their mesohyl, providing the host with a means of chemical defence against predation and microbial infection. Here, we report an intriguing case of chemically mediated symbiosis between the renieramycin-containing sponge Haliclona sp.
C Lee et al.
Biochemistry and molecular biology international, 31(5), 797-805 (1993-12-01)
An enzyme fraction with catalytic activities for the biosynthesis of the pipecolic acid containing cyclopeptolide SDZ 90-215 was partially purified and characterized from the genus Septoria. The crude cell homogenate was subjected to polyethyleneimine precipitation, ammonium sulfate precipitation and FPLC
S E Shoelson et al.
The Journal of biological chemistry, 264(14), 7831-7836 (1989-05-15)
The receptors for insulin and epidermal growth factor undergo tyrosine autophosphorylation in response to ligand stimulation, while pp60v-src is an unregulated tyrosine kinase. In this report we show that each of the kinases phosphorylates an exogenous peptide that corresponds to
Amersham Prize winner. Expanding the genetic code.
Lei Wang
Science (New York, N.Y.), 302(5645), 584-585 (2003-10-25)

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