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Sigma-Aldrich

Ethylenediamine-N,N′-diacetic acid

≥98%

Synonym(s):

EDDA, N,N′-Ethylenediglycine

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About This Item

Linear Formula:
HOOCCH2NHCH2CH2NHCH2COOH
CAS Number:
Molecular Weight:
176.17
Beilstein:
1778355
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

mp

224 °C (dec.) (lit.)

SMILES string

OC(=O)CNCCNCC(O)=O

InChI

1S/C6H12N2O4/c9-5(10)3-7-1-2-8-4-6(11)12/h7-8H,1-4H2,(H,9,10)(H,11,12)

InChI key

IFQUWYZCAGRUJN-UHFFFAOYSA-N

Application

Ethylenediamine-N,N′-diacetic acid (EDDA) is a chelating agent that can be used to synthesize:
  • Binary and ternary copper(II) complexes with potent proteasome inhibitory properties.
  • Pd(EDDA) complexes which can coordinate with amino acids, peptides, or DNA units.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Katarina Norén et al.
Journal of colloid and interface science, 319(2), 416-428 (2007-12-25)
The adsorption of amino acids onto mineral surfaces plays an important role in a wide range of areas, e.g., low-temperature aqueous geochemistry, bone formation and protein-bone interactions. In this work, the adsorption of three alpha aminoacids (sarcosine, MIDA and EDDA)
Tomokazu Yoshimura et al.
Journal of colloid and interface science, 339(1), 230-235 (2009-08-18)
Three anionic homologues of a novel partially fluorinated carboxylate-type anionic gemini surfactant, N,N'-di(3-perfluoroalkyl-2-hydroxypropyl)-N,N'-diacetic acid ethylenediamine (2C(n)(F) edda, where n represents the number of carbon atoms in the fluorocarbon chain (4, 6, and 8)) were synthesized. In these present gemini surfactants
Pornthep Sompornpisut et al.
Biophysical journal, 95(11), 5349-5361 (2008-08-05)
We present an approach for incorporating solvent accessibility data from electron paramagnetic resonance experiments in the structural refinement of membrane proteins through restrained molecular dynamics simulations. The restraints have been parameterized from oxygen (PiO(2)) and nickel-ethylenediaminediacetic acid (PiNiEdda) collision frequencies
Structural characterization, ROS-inductive and proteasome inhibitory properties of ternary and binary copper (II) complexes of N2- and N2O2-ligands.
Chan CW, et al.
Inorgorganica Chimica Acta, 450, 202-210 (2016)
Zhiwen Yuan et al.
Biodegradation, 19(1), 41-52 (2007-04-04)
Ethylenediaminetetraacetic acid (EDTA) and nitrilotriacetic acid (NTA) are widely used anthropogenic chelating agents for control of metal speciation and are ubiquitous in natural waters and wastewaters. This is the first report of systematic measurement of the growth yields of a

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