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152986

Sigma-Aldrich

1-Benzyl-4-hydroxypiperidine

96%

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Synonym(s):
1-Benzyl-4-piperidinol
Empirical Formula (Hill Notation):
C12H17NO
CAS Number:
Molecular Weight:
191.27
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

96%

form

solid

bp

127-128 °C/2 mmHg (lit.)

mp

61-63 °C (lit.)

SMILES string

OC1CCN(CC1)Cc2ccccc2

InChI

1S/C12H17NO/c14-12-6-8-13(9-7-12)10-11-4-2-1-3-5-11/h1-5,12,14H,6-10H2

InChI key

BPPZXJZYCOETDA-UHFFFAOYSA-N

Application

1-Benzyl-4-hydroxypiperidine was used as an alternative molecule to study the ligand concentration attached to the epoxy-activated Sepharose 6B.
Reactant for synthesis of:
Muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist
Fatty acid amide hydrolase inhibitors
PI3 kinase-alpha inhibitors
Flavonoid derivatives used as dual binding acetylcholinesterase inhibitors
Urotensin-II receptor antagonists
Rho kinase inhibitors

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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X Santarelli et al.
Journal of chromatography. B, Biomedical sciences and applications, 739(1), 63-72 (2000-04-01)
New pseudo-affinity chromatographic supports for penicillin acylase were prepared and evaluated with three different samples: pure penicillin acylase, industrial clarified feedstock and crude extract. The different gels were studied for their purification fold (three to six) and their recovery power

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