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Key Documents

149357

Sigma-Aldrich

2,5-Dihydroxybenzoic acid

98%

Synonym(s):

2,5-DHBA, DHB, Gentisic acid, Hydroquinonecarboxylic acid

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50 EA
CN¥3,012.56

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50 EA
CN¥3,012.56

About This Item

Linear Formula:
(HO)2C6H3CO2H
CAS Number:
Molecular Weight:
154.12
Beilstein:
2209119
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

CN¥3,012.56


Please contact Customer Service for Availability

Request a Bulk Order

Quality Level

Assay

98%

form

powder

mp

204-208 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(=O)c1cc(O)ccc1O

InChI

1S/C7H6O4/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,8-9H,(H,10,11)

InChI key

WXTMDXOMEHJXQO-UHFFFAOYSA-N

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1 of 4

This Item
F2256F6760FBS25
Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

500

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

composition

Dye content, 15%

composition

Dye content, ~20%

composition

-

composition

-

λmax

284 nm

λmax

-

λmax

-

λmax

-

ε (extinction coefficient)

≥3000 at 281-287 nm in water at 0.006 g/L

ε (extinction coefficient)

-

ε (extinction coefficient)

-

ε (extinction coefficient)

-

General description

Aspirin metabolite.

Application

2,5-Dihydroxybenzoic acid (2,5-DHBA) can be used:
  • As a matrix in the MALDI-TOF mass spectrometry analysis of the poly(styrene-co-pentafluorostyrene) copolymers.[1]
  • To prepare pharmacologically important 2,5-DBHA-gelatin conjugate, which can act as a polymer for the development of drug formulations.[2]
  • As a tridentate ligand to synthesize complexes of molybdenum by reacting with (PPh4)4Mo8O26.[3]
  • As a starting material in the total synthesis of landomycin A, an angucycline antibiotic.[4]

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Matthew T Briggs et al.
Rapid communications in mass spectrometry : RCM, 31(10), 825-841 (2017-03-09)
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) of the proteome of a tissue has been an established technique for the past decade. In the last few years, MALDI-MSI of the N-glycome has emerged as a novel MALDI-MSI technique. To assess
Polynuclear oxomolybdenum (VI) complexes of dihydroxybenzoic acids: Synthesis, spectroscopic and structure characterization of a tetranuclear catecholato-type coordinated 2, 3-dihydroxybenzoate and a novel tridentate salicylato-type coordinated 2, 5-dihydroxybenzoate trinuclear complex
Litos C, et al.
Polyhedron, 25(6), 1337-1347 (2006)
A 2, 5-Dihydroxybenzoic acid-gelatin conjugate: the synthesis, antiviral activity and mechanism of antiviral action against two alphaherpesviruses
Lisov A, et al.
Viruses, 7(10), 5343-5360 (2015)
Matrix-assisted laser desorption/ionization sample preparation optimization for structural characterization of poly (styrene-co-pentafluorostyrene) copolymers
Tisdale E, et al.
Analytica Chimica Acta, 808, 151-162 (2014)
Evgenia Tisdale et al.
Analytica chimica acta, 808, 151-162 (2013-12-29)
The influence of the sample preparation parameters (the choice of the matrix, matrix:analyte ratio, salt:analyte ratio) was investigated and optimal conditions were established for the MALDI time-of-flight mass spectrometry analysis of the poly(styrene-co-pentafluorostyrene) copolymers. These were synthesized by atom transfer

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