Skip to Content
Merck
CN
All Photos(3)

Documents

146625

Sigma-Aldrich

Bathocuproinedisulfonic acid disodium salt hydrate

Sign Into View Organizational & Contract Pricing
All Photos(3)
Empirical Formula (Hill Notation):
C26H18N2Na2O6S2 · xH2O
CAS Number:
1257642-74-2
Molecular Weight:
564.54 (anhydrous basis)
MDL number:
MFCD00149974
UNSPSC Code:
12352100
PubChem Substance ID:
24848788
NACRES:
NA.22

form

powder

mp

300 °C (lit.)

SMILES string

O.[Na+].[Na+].Cc1nc2c(ccc3c(-c4ccccc4)c(c(C)nc23)S([O-])(=O)=O)c(-c5ccccc5)c1S([O-])(=O)=O

InChI

1S/C26H20N2O6S2.2Na.H2O/c1-15-25(35(29,30)31)21(17-9-5-3-6-10-17)19-13-14-20-22(18-11-7-4-8-12-18)26(36(32,33)34)16(2)28-24(20)23(19)27-15;;;/h3-14H,1-2H3,(H,29,30,31)(H,32,33,34);;;1H2/q;2*+1;/p-2

InChI key

ZAGWMJUGRCMNGX-UHFFFAOYSA-L

General description

Bathocuproine disulfonic acid (BCDS) is a stable Cu+ chelator and BCDS-Cu+ inhibits the HIV-1 wild type protease as well as a mutant HIV-1 protease lacking cysteine. It is an extracellular copper chelator.

Application

Bathocuproinedisulfonic acid disodium salt hydrate was used as chelator in electron spin resonance spin trapping technique to study free radical generation in rats with acute sodium formate poisoning. It was used as reagent for determination of Cu and Cu-protein complexes.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Suzie Kang et al.
International journal of molecular sciences, 21(20) (2020-10-22)
Copper is an essential metal ion that performs many physiological functions in living organisms. Deletion of Afmac1, which is a copper-responsive transcriptional activator in A. fumigatus, results in a growth defect on aspergillus minimal medium (AMM). Interestingly, we found that
Monirul Islam et al.
Frontiers in plant science, 11, 325-325 (2020-05-07)
The Earth's magnetic field, defined as the geomagnetic field (GMF), is an unavoidable environmental factor for all living organisms. Variation in the GMF intensity was found to affect the content of some nutrients and their associated channels and transporters in
D A Davis et al.
Archives of biochemistry and biophysics, 322(1), 127-134 (1995-09-10)
The protease encoded by the human immunodeficiency virus-1 (HIV-1) is essential for processing viral polyproteins which contain the enzymes and structural proteins required for the infectious virus. It was previously found that cupric chloride, in the presence of dithiothreitol or
A E Dikalova et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(24), 13549-13553 (2001-11-22)
Electron spin resonance spectroscopy has been used to study free radical generation in rats with acute sodium formate poisoning. The in vivo spin-trapping technique was used with alpha-(4-pyridyl-1-oxide)-N-t-butylnitrone (POBN), which reacts with free radical metabolites to form radical adducts, which
M Matsushita et al.
Clinica chimica acta; international journal of clinical chemistry, 216(1-2), 103-111 (1993-07-16)
A method of protein determination has been developed which combines the biuret reaction and the copper(I)-bathocuproine chelate reaction. Protein in the specimen forms a Cu(2+)-protein chelate complex (biuret reaction) during the first step. Excess Cu2+ is reduced to Cu+ by
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service