146188
2-Hydroxy-5-methoxybenzoic acid
98%
Synonym(s):
5-Methoxysalicylic acid
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About This Item
Linear Formula:
CH3OC6H3(OH)CO2H
CAS Number:
Molecular Weight:
168.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-037-8
Beilstein/REAXYS Number:
2209647
MDL number:
Assay:
98%
Form:
powder
Quality Level
InChI key
IZZIWIAOVZOBLF-UHFFFAOYSA-N
InChI
1S/C8H8O4/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4,9H,1H3,(H,10,11)
SMILES string
COc1ccc(O)c(c1)C(O)=O
assay
98%
form
powder
mp
141-143 °C (lit.)
functional group
carboxylic acid
Related Categories
General description
2-Hydroxy-5-methoxybenzoic acid is matrix additive which enhances the electrical conductivity of the matrix crystal during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS).
Application
2-Hydroxy-5-methoxybenzoic acid was used to evaluate MALDI matrix/solvent combinations for intact spore mass spectrometry of Fusarium species.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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T Nishihata et al.
Diabetes, 30(12), 1065-1067 (1981-12-01)
Sodium 5-methoxysalicylate, previously shown to enhance the rectal absorption of several drugs, facilitates the absorption of insulin from the upper gastrointestinal tract, resulting in significantly elevated insulin levels and lowered glucose concentrations in the plasma of rats. Restricting the movement
Osmond D Rebello et al.
Frontiers in chemistry, 8, 138-138 (2020-03-19)
Changes in the abundance of antennary fucosylated glycans in human total plasma N-glycome (TPNG) have been associated with several diseases ranging from diabetes to various forms of cancer. However, it is challenging to address this important part of the human
Lucie Riglet et al.
eLife, 9 (2020-09-02)
Successful fertilization in angiosperms depends on the proper trajectory of pollen tubes through the pistil tissues to reach the ovules. Pollen tubes first grow within the cell wall of the papilla cells, applying pressure to the cell. Mechanical forces are
T Nishihata et al.
The Journal of pharmacy and pharmacology, 35(3), 148-151 (1983-03-01)
Sodium salicylate and 5-methoxysalicylate both increased the rectal absorption of insulin in dogs when co-administered with insulin in various formulations. Microenema formulations containing 4% gelatin showed the highest insulin bioavailability of the formulations studied whereas microenemas (without gelatin) and suppository
Lise Hafkenscheid et al.
Molecular & cellular proteomics : MCP, 16(2), 278-287 (2016-12-14)
Recently, we showed the unexpectedly high abundance of N-linked glycans on the Fab-domain of Anti-Citrullinated Protein Antibodies (ACPA). As N-linked glycans can mediate a variety of biological functions, we now aimed at investigating the structural composition of the Fab-glycans of
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