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Merck
CN

143219

4-Bromophenylhydrazine hydrochloride

99%

Synonym(s):

1-(4-Bromophenyl)hydrazine hydrochloride, 2-(4-Bromophenyl)hydrazinium chloride, 4-Bromophenylhydrazine monohydrochloride, p-Bromophenylhydrazine monohydrochloride

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About This Item

Linear Formula:
BrC6H4NHNH2·HCl
CAS Number:
622-88-8
Molecular Weight:
223.50
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24848576
MDL number:
MFCD00012941
Beilstein/REAXYS Number:
3565838

Key Documents

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Product Name

4-Bromophenylhydrazine hydrochloride, 99%

InChI

1S/C6H7BrN2.ClH/c7-5-1-3-6(9-8)4-2-5;/h1-4,9H,8H2;1H

SMILES string

Cl.NNc1ccc(Br)cc1

InChI key

RGGOWBBBHWTTRE-UHFFFAOYSA-N

assay

99%

form

powder

mp

220-230 °C (dec.) (lit.)

functional group

bromo
hydrazine

Quality Level

100

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Related Categories

Application

4-Bromophenylhydrazine hydrochloride was used as reagent in the synthesis of:
  • acylsulfonamides and acylsulfamides
  • 9-bromo-2-ethenyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
STBF6283V
MKBF9632V
S31274V
MKAA2806
07806BH

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Michael P Winters et al.
Bioorganic & medicinal chemistry letters, 18(6), 1926-1930 (2008-03-01)
A series of novel acylsulfonamide, acylsulfamide, and sulfonylurea bioisosteres of carboxylic acids were prepared as CXCR2 antagonists. Structure-activity relationships are reported for these series. One potent orally bioavailable inhibitor had excellent PK properties and was active in a lung injury
Xu Xie et al.
European journal of medicinal chemistry, 40(7), 655-661 (2005-06-07)
The introduction of side chains bearing epoxide motifs into the molecular scaffold of kenpaullone and 9-trifluoromethylpaullone led to improved antiproliferative activity of the novel derivatives for human tumor cell lines. The syntheses were accomplished applying Stille coupling for the introduction
Siva Doddi et al.
Journal of fluorescence, 26(6), 1939-1949 (2016-11-01)
We report the synthesis and characterization of a new fluorescent dyad SP-DPP-SP(9) via efficient palladium-catalyzed Sonogashira coupling of prop-2-yn-1-yl 3-(3',3'dimethyl-6-nitrospiro[chromene-2,2'-indolin]-1'-yl)propanoatespiropyran, SP(8), a well known photochromic accepter, with 3,6-bis(5-bromothiophen-2-yl)-2,5-bis((R)-2-ethylhexyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione, DPP(4), a highly fluorescent donor. Under visible light exposure the SP unit
Ilkoo Noh et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(3), 1700481-1700481 (2018-03-30)
A noninvasive and selective therapy, photodynamic therapy (PDT) is widely researched in clinical fields; however, the lower efficiency of PDT can induce unexpected side effects. Mitochondria are extensively researched as target sites to maximize PDT effects because they play crucial

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