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137456

Sigma-Aldrich

2-Ethyl-2-oxazoline

≥99%

Synonym(s):

2-Ethyl-4,5-dihydrooxazole, 2-Ethyloxazoline

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About This Item

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
10431-98-8
Molecular Weight:
99.13
EC Number:
233-912-4
MDL number:
MFCD00005302
UNSPSC Code:
12352100
PubChem Substance ID:
24848326
NACRES:
NA.22

Quality Level

100

Assay

≥99%

form

liquid

refractive index

n20/D 1.437 (lit.)

bp

128.4 °C (lit.)

mp

−62 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

SMILES string

CCC1=NCCO1

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

Related Categories

General description

2-Ethyl-2-oxazoline undergoes cationic ring opening graft polymerization using tosylated cellulose nanowhisker as macroinitiator.

Application

2-Ethyl-2-oxazoline (EtOx) was used in synthesis of block copolymers of EtOx and styrene by cationic ring-opening polymerization and atom transfer radical polymerization.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H302 + H312 + H332

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3

WGK

WGK 1

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

Certificates of Analysis (COA)

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Mohsen Salmanpour et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 136, 104941-104941 (2019-05-29)
SN-38 is the active metabolite of irinotecan, an FDA-approved chemotherapeutic agent indicated for colorectal carcinoma, which would not be clinically applicable due to its very poorly soluble and hydrolytic degradation properties. To overcome these limitations, it was proposed to conjugate
Abbas Dadkhah Tehrani et al.
Carbohydrate polymers, 97(1), 98-104 (2013-06-19)
The cellulose nanocrystals, prepared by acid hydrolysis of cotton linter, consisted of slender rods with an average length of 173 nm and diameter of 80 nm, respectively. The surface of obtained cellulose nanocrystals was chemically modified using tosyl chloride and
Synthesis of poly (2-ethyl-2-oxazoline)-b-poly (styrene) copolymers via a dual initiator route combining cationic ring-opening polymerization and atom transfer radical polymerization.
Becer CR, et al.
Macromolecules, 41(14), 5210-5215 (2008)
Luqiao Wen et al.
Drug development and industrial pharmacy, 46(2), 283-295 (2020-01-17)
In this study, we evaluated and screened the effects of the molecular weight (MW) and molar ratio of poly(2-ethyl-2-oxazoline)-cholesteryl methyl carbonate (PEtOz-CHMC) on the pH sensitivity, stability, and antitumor efficacy of liposomes. The pH sensitivity of PEtOz-CHMC with different MWs
Věra Mazánková et al.
Polymers, 12(11) (2020-11-19)
Polyoxazoline thin coatings were deposited on glass substrates using atmospheric pressure plasma polymerization from 2-ethyl-2-oxazoline vapours. The plasma polymerization was performed in dielectric barrier discharge burning in nitrogen at atmospheric pressure. The thin films stable in aqueous environments were obtained
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