130303
1,2-Dimethyl-3-nitrobenzene
97%
Synonym(s):
3-Nitro-o-xylene
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About This Item
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Assay
97%
97%
form
liquid
refractive index
n20/D 1.543 (lit.)
bp
245 °C (lit.)
mp
7-9 °C (lit.)
density
1.129 g/mL at 25 °C (lit.)
SMILES string
Cc1cccc(c1C)[N+]([O-])=O
InChI
1S/C8H9NO2/c1-6-4-3-5-8(7(6)2)9(10)11/h3-5H,1-2H3
InChI key
FVHAWXWFPBPFOS-UHFFFAOYSA-N
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Application
1,2-Dimethyl-3-nitrobenzene (3-Nitro-o-xylene) was used to prepare 2-methyl-3-nitrobenzylidene diacetate. It was also used to dissolve sodium-selective ligand.
Hazard Statements
Precautionary Statements
Hazard Classifications
Aquatic Chronic 2
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 2
Flash Point(F)
224.6 °F - closed cup
Flash Point(C)
107 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Science (New York, N.Y.), 203(4387), 1349-1351 (1979-03-30)
The sodium-selective ligand 1,1,1-tris[1(1)-(2(1)-oxa-4(1)-oxo-5(1)-aza-5(1)-methyl)dodecanyl]propane dissolved in 3-nitro-o-xylene containing a small amount of the lipophilic anion tetrachlorophenyl borate was used as a liquid ion-exchanger in sodium-selective microelectrodes. The microelectrodes gave rapid, stable responses that were linear functions of the logarithm of
Oxidation and Claisen condensation products of 3-nitro-o-xylene.
Journal of the Chemical Society. Perkin transactions 1, 14, 1935-1939 (1969-01-01)
The Journal of physiology, 597(2), 583-597 (2018-10-26)
Neuronal activity induces fluctuation in extracellular space volume, [K+ ]o and pHo , the management of which influences neuronal function The neighbour astrocytes buffer the K+ and pH and swell during the process, causing shrinkage of the extracellular space In
Glia, 69(1), 28-41 (2020-06-09)
The mammalian brain consists of 80% water, which is continuously shifted between different compartments and cellular structures by mechanisms that are, to a large extent, unresolved. Aquaporin 4 (AQP4) is abundantly expressed in glia and ependymal cells of the mammalian
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