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Safety Information

130214

Sigma-Aldrich

5-Nitroindoline

97%

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Empirical Formula (Hill Notation):
C8H8N2O2
CAS Number:
Molecular Weight:
164.16
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

mp

92-94 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc2NCCc2c1

InChI

1S/C8H8N2O2/c11-10(12)7-1-2-8-6(5-7)3-4-9-8/h1-2,5,9H,3-4H2

InChI key

WJQWYAJTPPYORB-UHFFFAOYSA-N

Application

5-Nitroindoline was used to prepare acetylated glucosylamines using the Suvorov procedure.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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Carmine Ostacolo et al.
Journal of medicinal chemistry, 63(1), 163-185 (2019-12-10)
Kv7 K+ channels represent attractive pharmacological targets for the treatment of different neurological disorders, including epilepsy. In this paper, 42 conformationally restricted analogues of the prototypical Kv7 activator retigabine have been synthesized and tested by electrophysiological patch-clamp experiments as Kv7
Substituted glucosylamines containing the indole nucleus.
Magnin AA, et al.
Tetrahedron, 25(18), 4543-4550 (1969)

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