129941
1-Methyl-3-nitro-1-nitrosoguanidine
97%
Synonym(s):
N-Methyl-N′-nitro-N-nitrosoguanidine, Diazomethane precursor, MNNG
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About This Item
Linear Formula:
CH3N(NO)C(=NH)NHNO2
CAS Number:
Molecular Weight:
147.09
Beilstein:
1779490
EC Number:
MDL number:
UNSPSC Code:
12352000
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Assay
97%
mp
118 °C (dec.) (lit.)
SMILES string
CN(N=O)C(=N)N[N+]([O-])=O
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Application
Very potent mutagen. Precursor to diazomethane. For preparation and reactions of diazomethane.
Biochem/physiol Actions
Environmental mutagen and carcinogen; used to induce gastric cancer in mice.
Other Notes
Contains 1-methyl-3-nitroguanidine
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Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Carc. 1B - Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2
Storage Class Code
4.1A - Other explosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
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Aldrichimica Acta, 16, 3-3 (1983)
Roberta Meschini et al.
Mutation research. Genetic toxicology and environmental mutagenesis, 793, 79-85 (2015-11-02)
We evaluated the protective effects of Gentiana lutea extracts (GLEx) and 6-Gingerol (6-G) on clastogenicity of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and 7,12-dimethylbenz(α) anthracene (DMBA) in vitro on HepG2 cells using the frequencies of induced micronuclei (MN) as the end point. Pre-, post-
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