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Key Documents

Safety Information

128937

Sigma-Aldrich

N-Benzylaniline

99%

Synonym(s):

N-Phenylbenzylamine

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About This Item

Linear Formula:
C6H5CH2NHC6H5
CAS Number:
Molecular Weight:
183.25
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

99%

bp

306-307 °C (lit.)

mp

35-38 °C (lit.)

density

1.061 g/mL at 25 °C (lit.)

SMILES string

C(Nc1ccccc1)c2ccccc2

InChI

1S/C13H13N/c1-3-7-12(8-4-1)11-14-13-9-5-2-6-10-13/h1-10,14H,11H2

InChI key

GTWJETSWSUWSEJ-UHFFFAOYSA-N

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Application

N-benzylaniline was used as a potent inhibitor of lignostilbene-α,β-dioxygenase.

replaced by

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Sun-Young Han et al.
Journal of enzyme inhibition and medicinal chemistry, 18(3), 279-283 (2003-09-26)
Lignostilbene-alpha,beta-dioxygenase (LSD, EC 1.13.11.43) is involved in oxidative cleavage of the central double bond of lignostilbene to form the corresponding aldehydes by a mechanism similar to those of 9-cis-epoxycarotenoid dioxygenase and beta-carotene 15,15'-dioxygenase, key enzymes in abscisic acid biosynthesis and
Yung-Hung Chang et al.
Dalton transactions (Cambridge, England : 2003), (5)(5), 861-867 (2009-01-22)
Both saturated and unsaturated N-benzyl substituted heterocyclic carbene (NHC) iridum(i) complexes were synthesized. The unsaturated carbene complex [(un-NHC-Bn)Ir(CO)(2)Cl] in the cis form was prepared via the carbene transfer from the corresponding silver complex to [Ir(COD)(2)Cl](2) followed by ligand substitution with
Identification of a new metabolite after incubation of N-benzylaniline with rabbit liver microsomes.
H M Ali et al.
Journal of chromatography, 202(2), 287-293 (1980-12-19)
J W Gorrod et al.
Xenobiotica; the fate of foreign compounds in biological systems, 15(12), 1021-1031 (1985-12-01)
Using direct specific analytical techniques microsomal metabolism of N-benzyl-4-substituted anilines has been investigated and found to include both N- and C-oxidation. N-Debenzylation was observed with all substrates and species examined. N-Oxidation usually yielded aryl nitrones, although the N-hydroxy derivative of
Synthesis and structure-activity relationships of a class of sodium iodide symporter function inhibitors.
Fanny Waltz et al.
ChemMedChem, 6(10), 1775-1777 (2011-07-14)

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