All Photos(1)
Synonym(s):
4-MU, 4-Methylumbelliferone, Coumarin 4
Empirical Formula (Hill Notation):
C10H8O3 · H2O
CAS Number:
Molecular Weight:
194.18
Beilstein:
142217
EC Number:
MDL number:
UNSPSC Code:
12352103
Recommended Products
Assay
97%
mp
188.5-190 °C (lit.)
λmax
≤221 nm
SMILES string
CC1=CC(=O)Oc2cc(O)ccc12
Looking for similar products? Visit Product Comparison Guide
Application
Standard for the fluorometric determination of enzyme activity.
Suitable as laser dye
Other Notes
This product has been replaced by M1381-ALDRICH | 4-Methylumbelliferone ≥98%
replaced by
Product No.
Description
Pricing
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
K Takagaki et al.
Journal of biochemical and biophysical methods, 19(2-3), 207-214 (1989-08-01)
The present paper describes a fluorometric assay for galactosaminoglycan-degrading endo-beta-xylosidase, utilizing glycosaminoglycan chains bearing a 4-methylumbelliferyl group at the reducing terminus as a substrate. This fluorogenic substrate is synthesized by human skin fibroblasts cultured in the presence of a fluorogenic
Laura Piccagli et al.
Bioorganic & medicinal chemistry, 18(23), 8341-8349 (2010-10-29)
In the present study, a structured-based virtual screening (VS) of differently substituted furocoumarins and analogues has been carried out against nuclear factor kappa B (NF-κB), with the objective of selecting molecules able to inhibit the binding of this transcription factor
Joanna Trykowska Konc et al.
European journal of medicinal chemistry, 46(6), 2252-2263 (2011-03-29)
A series of novel O-aminoalkyl substituted 7-hydroxycoumarins were synthesized and evaluated for antibacterial and anticancer toxicity. Two different synthetic procedures, conventional and microwave assisted were used, and the structures of the compounds were confirmed by IR, 1H, 13C NMR and
Koichiro Harada et al.
Bioorganic & medicinal chemistry letters, 20(1), 272-275 (2009-12-04)
The synthesis and SAR studies of 3- and 4-substituted 7-hydroxycoumarins as novel 17beta-HSD3 inhibitors are discussed. The most potent compounds from this series exhibited low nanomolar inhibitory activity with acceptable selectivity versus other 17beta-HSD isoenzymes and nuclear receptors.
Yuan Shi et al.
Bioorganic & medicinal chemistry letters, 21(3), 956-960 (2011-01-11)
A series of new coumarin-based 1,2,4-triazole derivatives were designed, synthesized and evaluated for their antimicrobial activities in vitro against four Gram-positive bacteria (Staphylococcus aureus, MRSA, Bacillus subtilis and Micrococcus luteus), four Gram-negative bacteria (Escherichia coli, Proteus vulgaris, Salmonella typhi and
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service