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123048

Sigma-Aldrich

5-Amino-1-pentanol

≥92.0% (GC)

Synonym(s):

5-Aminopentanol

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About This Item

Linear Formula:
NH2(CH2)5OH
CAS Number:
2508-29-4
Molecular Weight:
103.16
Beilstein:
1732302
EC Number:
219-718-2
MDL number:
MFCD00008237
UNSPSC Code:
12352100
PubChem Substance ID:
24847516
NACRES:
NA.22

Quality Level

200

Assay

≥92.0% (GC)

form

solid

refractive index

n20/D 1.4615 (lit.)

bp

120-122 °C/16 mmHg (lit.)

mp

33-35 °C (lit.)

density

0.949 g/mL at 25 °C (lit.)

SMILES string

NCCCCCO

InChI

1S/C5H13NO/c6-4-2-1-3-5-7/h7H,1-6H2

InChI key

LQGKDMHENBFVRC-UHFFFAOYSA-N

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General description

5-Amino-1-pentanol undergoes facile intramolecular cyclocondensation with piperidine and methyl or ethyl piperidine in the presence of methanol or ethanol over zeolite catalyst.

Application

5-Amino-1-pentanol has been used in the synthesis of S-glycosyl amino-acid building blocks. It has been used as starting reagent in the synthesis of aminofunctionalized 4-chloro-2,2′:6′,2′′-terpyridine.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H314

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Thomas Ziegler et al.
Nature protocols, 1(4), 1987-1994 (2007-05-10)
Complex glycosylation patterns on cell surfaces are involved in many fundamental biological processes like specific cell-cell interactions and signal transduction. Furthermore, the glycon part of glycopeptides and glycosylated proteins play a crucial role in numerous ligand-receptor interactions of biological significance.
4'-Functionalized 2, 2′ : 6′, 2′′-terpyridines as building blocks for supramolecular chemistry and nanoscience.
Schubert US,et al.
Tetrahedron, 42(28), 4705-4707 (2001)
Duho Cho et al.
Micromachines, 11(6) (2020-07-08)
A stretchable printed circuit board (PCB), which is an essential component of next-generation electronic devices, should be highly stretchable even at high levels of integration, as well as durable under repetitive stretching and patternable. Herein, an island-structured stretchable PCB composed
Zeolite catalysed intramolecular cyclization of 5-amino-1-pentanol to piperidine bases.
Reddy BN, et al.
Applied Catalysis A: General, 119(1), 23-32 (1994)
Ahmed A Eltoukhy et al.
ACS nano, 8(8), 7905-7913 (2014-07-11)
Despite intensive research effort, the rational design of improved nanoparticulate drug carriers remains challenging, in part due to a limited understanding of the determinants of nanoparticle entry and transport in target cells. Recent studies have shown that Niemann-Pick C1 (NPC1)
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