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Merck
CN

119660

Tris(2-chloroethyl) phosphate

97%

Synonym(s):

Phosphoric acid tris(2-chloroethyl) ester

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About This Item

Linear Formula:
(ClCH2CH2O)3P(O)
CAS Number:
115-96-8
Molecular Weight:
285.49
NACRES:
NA.22
PubChem Substance ID:
24847295
UNSPSC Code:
12352100
EC Number:
204-118-5
MDL number:
MFCD00000967
Assay:
97%

Key Documents

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InChI key

HQUQLFOMPYWACS-UHFFFAOYSA-N

InChI

1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2

SMILES string

ClCCOP(=O)(OCCCl)OCCCl

vapor pressure

<10 mmHg ( 25 °C)

assay

97%

refractive index

n20/D 1.472 (lit.)

bp

192 °C/10 mmHg (lit.)

solubility

H2O: soluble 7.82 g/L

density

1.39 g/mL at 25 °C (lit.)

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General description

Tris(2-chloroethyl) phosphate is used as a flame retardant in plastics, especially inflexible foams used in automobiles and furniture and in rigid foams used for building insulation.

Application

Tris(2-chloroethyl) phosphate was used in dynamic air sampling of airborne organophosphate triesters using a solid-phase microextraction device.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

449.6 °F - closed cup

flash_point_c

232 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM5665
MKCB1019V
U08057V
S25669V
S25669

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T Umezu et al.
Toxicology and applied pharmacology, 148(1), 109-116 (1998-02-18)
The present study was conducted to clarify the acute effect of tris(2-chloroethyl)phosphate (TRCP), an organophosphate flame-retardant, on spontaneous ambulatory activity (AA) in male ICR mice and to examine the neurochemical mechanism of this effect. Single dose administration of 200 mg/kg
Peter F Moore et al.
Veterinary dermatology, 24(1), 204-211 (2013-01-22)
Cutaneous T-cell lymphoma (CTCL) in dogs is a heterogeneous disease complex, which consists of nonepitheliotropic (NE) and epitheliotropic forms. These lymphomas are readily recognized by the presence of dominant populations of cytologically atypical lymphocytes. The objective of this study was
G Ingerowski et al.
Indoor air, 11(3), 145-149 (2001-08-28)
The chlorinated organo-phosphate triesters, tris(2-chloroethyl)-phosphate (TCEP) and tris(monochloroisopropyl)-phosphate (TCPP), are employed in consumer articles for indoor usage, e.g. flame retardants and plasticizers in foam material as well as in paints, varnishes and wallpapers. As a result of this widespread usage
TRIS (2-CHLOROETHYL) PHOSPHATE
IARC Monographs, 71, 1543-1548 (1990)
D W Herr et al.
Drug metabolism and disposition: the biological fate of chemicals, 19(2), 436-442 (1991-03-01)
Tris(2-chloroethyl) phosphate (TRCP) is a flame retardant that has a wide variety of industrial applications. In subchronic studies, oral administration of TRCP to rats and mice has been reported to produce dose-, sex-, and species-dependent lesions in the hippocampal brain
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