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Merck
CN

113727

Norphenylephrine hydrochloride

98%

Synonym(s):

α-Aminomethyl-3-hydroxybenzyl alcohol hydrochloride, 3,α-Dihydroxyphenethylamine hydrochloride, Norfenefrine hydrochloride

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About This Item

Linear Formula:
HOC6H4CH(CH2NH2)OH · HCl
CAS Number:
Molecular Weight:
189.64
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
225-323-6
MDL number:
Assay:
98%
Form:
solid
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InChI key

OWMFSWZUAWKDRR-UHFFFAOYSA-N

InChI

1S/C8H11NO2.ClH/c9-5-8(11)6-2-1-3-7(10)4-6;/h1-4,8,10-11H,5,9H2;1H

SMILES string

Cl.NCC(O)c1cccc(O)c1

assay

98%

form

solid

mp

162-164 °C (lit.)

functional group

amine, hydroxyl

Quality Level

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Application

Norphenylephrine hydrochloride was used in the study of the effects of phenylephrine on the isolated heart of rabbit.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

监管及禁止进口产品
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J C David et al.
Journal of neurochemistry, 53(1), 149-154 (1989-07-01)
Functions of octopamine in the mammalian brain are still not well known. An important aspect of this problem is the relationship between octopamines and catecholamines. Previous data have shown that their respective ontogenic evolutions are not parallel. Do the changes
M Maeda et al.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 41(5), 463-469 (1990-01-01)
[11C]-p- and m-octopamine hydrochloride were synthesized from [11C]HCN in a two-step sequence. Chemical and enzymatic approaches were used for the formation of the [11C]cyanohydrin intermediates as the key step. Isolated radiochemical yields of 0.7-2.3% at the end-of-synthesis were obtained with
H Y Aboul-Enein et al.
Biomedical chromatography : BMC, 11(1), 7-10 (1997-01-01)
A direct, isocratic high-performance liquid chromatographic method is described for the enantiomeric resolution of a number of phenylalkylamines, namely, racemic cathinone, amphetamine, norephedrine, and norphenylephrine, without sample derivatization. The separations were achieved on an S-18-crown-6-ether chiral stationary phase known as
W Klosa et al.
Zeitschrift fur Geburtshilfe und Perinatologie, 196(1), 21-25 (1992-01-01)
Hypotension in pregnancy represents an often underestimated danger for mother and fetus. Several investigators have described an increased incidence of miscarriages, premature delivery and small for date babies. In a first study 10 pregnant women with hypotension and severe orthostatic
Yan Xiong et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(3), 829-833 (2006-10-28)
A new chiral hydrogenated salen catalyst has been developed for the asymmetric Henry reaction which produces the expected products in moderate to high yields (up to 98 %) with excellent enantioselectivities (up to 96 % ee). A variety of aromatic

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