Key Documents

View All Documentation

10895

Ethyl 2-chloroacetoacetate

Name: Ethyl 2-chloroacetoacetate
Brand: ALDRICH

Wacker Chemie AG, ≥96% (GC)

Synonym(s):

2-Cl-ACE

Select a Size

Change View

About This Item

Linear Formula:

CH₃COCHClCOOC₂H₅

CAS Number:

609-15-4

Molecular Weight:

164.59

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

57646831

EC Number:

210-180-4

Beilstein/REAXYS Number:

774278

MDL number:

MFCD00009141

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

assay

≥96% (GC)

manufacturer/tradename

Wacker Chemie AG

refractive index

n20/D 1.441 (lit.)

bp

107 °C/14 mmHg (lit.)

density

1.19 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)C(Cl)C(C)=O

InChI

1S/C6H9ClO3/c1-3-10-6(9)5(7)4(2)8/h5H,3H2,1-2H3

InChI key

RDULEYWUGKOCMR-UHFFFAOYSA-N

Description

Application

Ethyl 2-chloroacetoacetate was used to study reductive dechlorination of β-keto ester ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae.

Biochem/physiol Actions

Ethyl 2-chloroacetoacetate reacts with thiosemicarbazones to form heterocyclic substituted thiophene derivatives having non-steroidal anti-inflammatory activity.

Other Notes

prices for bulk quantities on request

pictograms

GHS05,GHS07,GHS09

signalword

Danger

hcodes

H302,H314,H335,H400

pcodes

P261 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

179.6 °F

flash_point_c

82 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and antiinflammatory activity of novel 2, 5-disubstituted thiophene derivatives.

Badr SMI.

Turkish Journal of Chemistry, 35(1), 131-143 (2011)

Analysis of inhibitors of the site-specific recombination reaction mediated by Tn3 resolvase.

P M Flanagan et al.

Journal of molecular biology, 206(2), 295-304 (1989-03-20)

The Tn3-encoded resolvase protein promotes a site-specific recombination reaction between two directly repeated copies of the recombination site res. Several inhibitors that block this event in vitro have been isolated. In this study four of these inhibitors were tested on

Fungal aerobic reductive dechlorination of ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae: mechanism of a novel type of microbial dehalogenation.

Gerhard Jörg et al.

Chembiochem : a European journal of chemical biology, 5(1), 87-92 (2003-12-26)

Saccharomyces cerevisiae reduces the beta-keto ester ethyl 2-chloroacetoacetate to the respective chiral cis- and trans-beta-hydroxy esters. In the course of chiral reduction, competing dehalogenation of the xenobiotic substrate to ethyl acetoacetate occurs, in a reaction mediated by cytosolic glutathione (GSH).

Global Trade Item Number

SKU	GTIN
307610-50G	04061826673706
307610-250G	04061826673690