All Photos(3)
Synonym(s):
1,2-Diamino-4-nitrobenzene
Linear Formula:
O2NC6H3(NH2)2
CAS Number:
Molecular Weight:
153.14
Beilstein:
608106
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39030501
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
98%
mp
199-201 °C (lit.)
solubility
1 N HCl: ethanol, 1:1: soluble 50 mg/mL
SMILES string
Nc1ccc(cc1N)[N+]([O-])=O
InChI
1S/C6H7N3O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,7-8H2
InChI key
RAUWPNXIALNKQM-UHFFFAOYSA-N
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Related Categories
Application
4-Nitro-o-phenylenediamine was used to study the in vitro activation of 4-nitro-o-phenylenediamine into a potent mutagen in Salmonella typhimurium strain TA98 .
Biochem/physiol Actions
4-Nitro-o-phenylenediamine is a direct-acting mutagen.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Skin Sens. 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Y H Shon et al.
Journal of ethnopharmacology, 77(1), 103-109 (2001-08-03)
Extracts from Phellinus linteus, Phellinus igniarius, and Agrocybe cylindracea have been tested for their antimutagenic properties against direct-acting mutagens [4-nitro-o-phenylenediamine (NPD) and sodium azide (NaN(3))] and indirect-acting mutagens [2-aminofluorene (2-AF) and benzo[a]pyrene (B[a]P)], using the Salmonella typhimurium tester strains TA
Marcos Felipe de Oliveira Galvão et al.
Environmental pollution (Barking, Essex : 1987), 233, 960-970 (2017-10-17)
Emissions from burning of biomass in the Amazon region have adverse effects on the environment and human health. Herein, particulate matter (PM) emitted from biomass burning in the Amazon region during two different periods, namely intense and moderate, was investigated.
Talat Baran et al.
International journal of biological macromolecules, 161, 1559-1567 (2020-08-14)
Removal of organic pollutants such as aromatic nitro compounds and dyes from wastewaters is very significant for environment, and the best strategy is their reduction/degradation in the presence of a metal catalyst. In this study, a new palladium nanocatalyst (GA-Sch-Pd)
S J Kaur et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38(12), 1113-1119 (2000-10-18)
A fraction isolated from Terminalia arjuna was studied for its antimutagenic effect against 4-nitro-o-phenylenediamine (NPD) in TA98, sodium azide in TA100 and 2-aminofluorene (2AF, S9-dependent), a promutagen, in both TA98 and TA 100 tester strains of Salmonella typhimurium using the
K Kaur et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 40(10), 1475-1482 (2002-10-22)
The antimutagenic effect of benzene, chloroform, acetone and methanol fractions from Terminalia arjuna, a well-known medicinal plant, was determined against Acid Black dye, 2-aminofluorene (2AF) and 4-nitro-o-phenylenediamine (NPD) in TA98 Frameshift mutagen tester strain of Salmonella typhimurium. Among the different
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