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Key Documents

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108898

Sigma-Aldrich

4-Nitro-o-phenylenediamine

98%

Synonym(s):

1,2-Diamino-4-nitrobenzene

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50 UNITS
¥453.31
250 UNITS
¥918.93
2500 UNITS
¥7,609.22

About This Item

Linear Formula:
O2NC6H3(NH2)2
CAS Number:
99-56-9
Molecular Weight:
153.14
Beilstein:
608106
EC Number:
202-766-3
MDL number:
MFCD00007724
UNSPSC Code:
12352100
eCl@ss:
39030501
PubChem Substance ID:
24846835
NACRES:
NA.22

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Quality Level

100

Assay

98%

mp

199-201 °C (lit.)

solubility

1 N HCl: ethanol, 1:1: soluble 50 mg/mL

functional group

nitro

SMILES string

Nc1ccc(cc1N)[N+]([O-])=O

InChI

1S/C6H7N3O2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H,7-8H2

InChI key

RAUWPNXIALNKQM-UHFFFAOYSA-N

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JumpStart™ REDTaq® DNA Polymerase Hot-start Taq enzyme with inert dye, 10X buffer included

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JumpStart™ REDAccuTaq® LA DNA Polymerase Long and accurate hot-start Taq with inert dye, 10X buffer included

D1313

JumpStart™ REDAccuTaq® LA DNA Polymerase

REDTaq® SuperPak™ DNA Polymerase Taq for routine PCR with inert dye; with 10X buffer & dNTP mix

D6063

REDTaq® SuperPak™ DNA Polymerase

REDTaq ® DNA 聚合酶 Taq for routine PCR with inert dye, 10X buffer included

D4309

REDTaq ® DNA 聚合酶

form

liquid

form

liquid

form

liquid

form

liquid

suitability

suitable for PCR

suitability

suitable for PCR

suitability

suitable for PCR

suitability

suitable for PCR

concentration

1 unit/μL

concentration

1 unit/μL

concentration

1 unit/μL

concentration

1 unit/μL

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Application

4-Nitro-o-phenylenediamine was used to study the in vitro activation of 4-nitro-o-phenylenediamine into a potent mutagen in Salmonella typhimurium strain TA98 [1].

Biochem/physiol Actions

4-Nitro-o-phenylenediamine is a direct-acting mutagen[2].

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000421974
    0000421974
    0000368905
    0000362590
    0000362590

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    Nahid Mashkouri Najafi et al.
    Analytica chimica acta, 714, 82-88 (2012-01-17)
    Herein, ultrasound-assisted emulsification microextraction (USAEME) and dispersive liquid-liquid microextraction (DLLME) methods based on applying low-density organic solvents have been critically compared for the speciation of inorganic selenium, Se(IV) (selenite) and Se(VI) (selenate) in environmental water samples by gas chromatography-flame ionization
    J M Gentile et al.
    Mutation research, 250(1-2), 79-86 (1991-09-01)
    Chlorophyllin, the sodium and copper salt of chlorophyll, chlorophyll a, and chlorophyll b were tested for their ability to inhibit the mutagenic activity of the direct-acting mutagen 4-nitro-o-phenylenediamine (NOP) and its plant-activated mutagenic enhancement. All three forms of chlorophyll were
    S J Toering et al.
    Mutation research, 361(2-3), 81-87 (1996-12-12)
    Aromatic amines are activated into mutagens by both animal and plant systems. For plant-activated aromatic amines an important step in this process involves peroxidase enzymes. 4-nitro-o-phenylenediamine (NOP) is a well known direct-acting mutagen that can be enhanced in mutagenic potency
    Marcos Felipe de Oliveira Galvão et al.
    Environmental pollution (Barking, Essex : 1987), 233, 960-970 (2017-10-17)
    Emissions from burning of biomass in the Amazon region have adverse effects on the environment and human health. Herein, particulate matter (PM) emitted from biomass burning in the Amazon region during two different periods, namely intense and moderate, was investigated.
    Y H Shon et al.
    Journal of ethnopharmacology, 77(1), 103-109 (2001-08-03)
    Extracts from Phellinus linteus, Phellinus igniarius, and Agrocybe cylindracea have been tested for their antimutagenic properties against direct-acting mutagens [4-nitro-o-phenylenediamine (NPD) and sodium azide (NaN(3))] and indirect-acting mutagens [2-aminofluorene (2-AF) and benzo[a]pyrene (B[a]P)], using the Salmonella typhimurium tester strains TA
    View All Related Papers

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