All Photos(2)

Documents

108073

8-Hydroxyquinoline hemisulfate salt hemihydrate

Name: 8-Hydroxyquinoline hemisulfate salt hemihydrate
Brand: ALDRICH

98%

Synonym(s):

8-Quinolinol hemisulfate, 8-Quinolinol sulfate (2:1) monohydrate

Sign Into View Organizational & Contract Pricing

All Photos(2)

About This Item

Empirical Formula (Hill Notation):

C₉H₇NO · 0.5H₂O₄S · 0.5H₂O

CAS Number:

207386-91-2

Molecular Weight:

203.20

EC Number:

205-137-1

MDL number:

MFCD00149610

UNSPSC Code:

12352100

PubChem Substance ID:

24846798

NACRES:

NA.22

Quality Level

200

Assay

98%

mp

176-179 °C (lit.)

solubility

H₂O: soluble 100 mg/mL, clear to slightly hazy, yellow to orange

SMILES string

[H]O[H].OS(O)(=O)=O.Oc1cccc2cccnc12.Oc3cccc4cccnc34

InChI

1S/2C9H7NO.H2O4S.H2O/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4;/h2*1-6,11H;(H2,1,2,3,4);1H2

InChI key

BNCXJZDIJIVJJO-UHFFFAOYSA-N

Related Categories

Heterocyclic Building Blocks

Biochem/physiol Actions

It is a potential copper ligand and is a tested effective proteasome inhibitor.

Preparation Note

8-Hydroxyquinoline hemisulfate salt hemihydrate dissolves in water at a concentration of 100 mg/ml to form a clear to slightly hazy, yellow to yellow-orange coloured solution.

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells.

Kenyon G Daniel et al.

Biochemical pharmacology, 67(6), 1139-1151 (2004-03-10)

Here we report that organic copper complexes can potently and selectively inhibit the chymotrypsin-like activity of the proteasome in vitro and in vivo. Several copper compounds, such as NCI-109268 and bis-8-hydroxyquinoline copper(II) [Cu(8-OHQ)(2)], can inhibit the chymotrypsin-like activity of purified

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service