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107344

Carbon tetrachloride

99%

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Synonym(s):
Tetrachloromethane
Empirical Formula (Hill Notation):
CCl4
CAS Number:
Molecular Weight:
153.82
Beilstein:
1098295
EC Number:
MDL number:
PubChem Substance ID:

vapor density

5.32 (vs air)

vapor pressure

143 mmHg ( 30 °C)
91 mmHg ( 20 °C)

Assay

99%

refractive index

n20/D 1.460 (lit.)

bp

76-77 °C (lit.)

mp

−23 °C (lit.)

density

1.594 g/mL at 25 °C (lit.)

SMILES string

ClC(Cl)(Cl)Cl

InChI

1S/CCl4/c2-1(3,4)5

InChI key

VZGDMQKNWNREIO-UHFFFAOYSA-N

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Pictograms

Skull and crossbonesHealth hazard

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 2 - Ozone 1 - Skin Sens. 1B - STOT RE 1 Inhalation

Target Organs

Liver,Kidney

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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J D Coombes et al.
Gut, 64(7), 1120-1131 (2014-06-07)
Chronic liver injury triggers a progenitor cell repair response, and liver fibrosis occurs when repair becomes deregulated. Previously, we reported that reactivation of the hedgehog pathway promotes fibrogenic liver repair. Osteopontin (OPN) is a hedgehog-target, and a cytokine that is
Kristina Søborg Pedersen et al.
Molecules (Basel, Switzerland), 25(5) (2020-03-07)
Despite promising anti-cancer properties in vitro, all titanium-based pharmaceuticals have failed in vivo. Likewise, no target-specific positron emission tomography (PET) tracer based on the radionuclide 45Ti has been developed, notwithstanding its excellent PET imaging properties. In this contribution, we present
Samar Basu
Toxicology, 189(1-2), 113-127 (2003-06-25)
Hepatic injury through carbon tetrachloride (CCl(4)) induced lipid peroxidation is well known and has been extensively used in the experimental models to understand the cellular mechanisms behind oxidative damage and further to evaluate the therapeutic potential of drugs and dietary
Mark A Barnes et al.
Journal of leukocyte biology, 97(1), 161-169 (2014-11-16)
Recruitment of peripheral monocytes to the liver is a key contributor to the response to injury. MIF can act as a chemokine and cytokine, regulating innate immune responses in many tissues and cell types. We hypothesized that MIF contributes to
Inge Mannaerts et al.
PloS one, 8(1), e55786-e55786 (2013-02-06)
The conversion of a quiescent vitamin A storing hepatic stellate cell (HSC) to a matrix producing, contractile myofibroblast-like activated HSC is a key event in the onset of liver disease following injury of any aetiology. Previous studies have shown that

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