106577
2-Iodohippuric acid
98%
Synonym(s):
N-(2-Iodobenzoyl)glycine
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About This Item
Linear Formula:
IC6H4CONHCH2CO2H
CAS Number:
Molecular Weight:
305.07
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-693-5
Beilstein/REAXYS Number:
1877943
MDL number:
InChI key
CORFWQGVBFFZHF-UHFFFAOYSA-N
InChI
1S/C9H8INO3/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)
SMILES string
OC(=O)CNC(=O)c1ccccc1I
assay
98%
reaction suitability
reaction type: solution phase peptide synthesis
mp
170-172 °C (lit.)
Quality Level
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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W M Michels et al.
Clinical nephrology, 72(5), 337-343 (2009-10-30)
Measuring GFR using exogenous markers without a bladder catheter, errors can be easily made due to incomplete urine collection. The aim was to quantify agreement for 125I-iothalamate GFR measurements with and without a correction for inaccurate urine collection using 131I-hippuran.
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(4), 578-584 (2013-02-21)
The pharmacokinetics of the tricarbonyl core radiopharmaceutical (99m)Tc(CO)3-nitrilotriacetic acid ((99m)Tc(CO)3(NTA)) in rats and subjects with normal renal function are comparable to those of (131)I-o-iodohippuran ((131)I-OIH), the radiopharmaceutical gold standard for the measurement of effective renal plasma flow. Our objective was
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 45(5), 885-891 (2004-05-12)
99mTc-Mercaptoacetyltriglycine ((99m)Tc-MAG3) and (99m)Tc-L,L-ethylenedicysteine ((99m)Tc-LL-EC) are useful renal radiopharmaceuticals; however, both agents have renal clearances less than that of (131)I-orthoiodohippurate ((131)I-OIH), and (99m)Tc-LL-EC exists in dianionic and monoanionic forms at physiologic pH. In an effort to develop a superior (99m)Tc
Gopal Pathuri et al.
Nuclear medicine communications, 32(10), 908-912 (2011-08-31)
We recently identified p-[(18)F]fluorohippurate ([(18)F]PFH) as a potential positron emission tomography (PET) renal agent. The objective of this study was to compare renogram parameters of [(18)F]PFH with o-[(125)I]iodohippurate ([(125)I]OIH) as a surrogate for the renal imaging gold standard (131)I-OIH and
Guillermo Lema et al.
Pediatric nephrology (Berlin, Germany), 21(10), 1446-1451 (2006-08-12)
We studied prospectively the perioperative changes of renal function in nine children undergoing cardiac surgery with cardiopulmonary bypass (CPB). Glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured with inulin and (131)I-hippuran clearances before CPB, during hypo
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