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106577

Sigma-Aldrich

2-Iodohippuric acid

98%

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Synonym(s):
N-(2-Iodobenzoyl)glycine
Linear Formula:
IC6H4CONHCH2CO2H
CAS Number:
Molecular Weight:
305.07
Beilstein:
1877943
EC Number:
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

reaction suitability

reaction type: solution phase peptide synthesis

mp

170-172 °C (lit.)

SMILES string

OC(=O)CNC(=O)c1ccccc1I

InChI

1S/C9H8INO3/c10-7-4-2-1-3-6(7)9(14)11-5-8(12)13/h1-4H,5H2,(H,11,14)(H,12,13)

InChI key

CORFWQGVBFFZHF-UHFFFAOYSA-N

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Related Categories

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Gopal Pathuri et al.
Nuclear medicine communications, 32(10), 908-912 (2011-08-31)
We recently identified p-[(18)F]fluorohippurate ([(18)F]PFH) as a potential positron emission tomography (PET) renal agent. The objective of this study was to compare renogram parameters of [(18)F]PFH with o-[(125)I]iodohippurate ([(125)I]OIH) as a surrogate for the renal imaging gold standard (131)I-OIH and
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 54(4), 578-584 (2013-02-21)
The pharmacokinetics of the tricarbonyl core radiopharmaceutical (99m)Tc(CO)3-nitrilotriacetic acid ((99m)Tc(CO)3(NTA)) in rats and subjects with normal renal function are comparable to those of (131)I-o-iodohippuran ((131)I-OIH), the radiopharmaceutical gold standard for the measurement of effective renal plasma flow. Our objective was
Andrew T Taylor et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 45(5), 885-891 (2004-05-12)
99mTc-Mercaptoacetyltriglycine ((99m)Tc-MAG3) and (99m)Tc-L,L-ethylenedicysteine ((99m)Tc-LL-EC) are useful renal radiopharmaceuticals; however, both agents have renal clearances less than that of (131)I-orthoiodohippurate ((131)I-OIH), and (99m)Tc-LL-EC exists in dianionic and monoanionic forms at physiologic pH. In an effort to develop a superior (99m)Tc
W M Michels et al.
Clinical nephrology, 72(5), 337-343 (2009-10-30)
Measuring GFR using exogenous markers without a bladder catheter, errors can be easily made due to incomplete urine collection. The aim was to quantify agreement for 125I-iothalamate GFR measurements with and without a correction for inaccurate urine collection using 131I-hippuran.
Guillermo Lema et al.
Pediatric nephrology (Berlin, Germany), 21(10), 1446-1451 (2006-08-12)
We studied prospectively the perioperative changes of renal function in nine children undergoing cardiac surgery with cardiopulmonary bypass (CPB). Glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured with inulin and (131)I-hippuran clearances before CPB, during hypo

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