105449
γ-Thiobutyrolactone
98%
Synonym(s):
4-Butyrothiolactone
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About This Item
Empirical Formula (Hill Notation):
C4H6OS
CAS Number:
Molecular Weight:
102.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
213-700-8
MDL number:
Assay:
98%
InChI key
KMSNYNIWEORQDJ-UHFFFAOYSA-N
InChI
1S/C4H6OS/c5-4-2-1-3-6-4/h1-3H2
SMILES string
O=C1CCCS1
assay
98%
refractive index
n20/D 1.523 (lit.)
bp
39-40 °C/1 mmHg (lit.)
solubility
THF: soluble
density
1.18 g/mL at 25 °C (lit.)
functional group
thioester
Quality Level
Related Categories
General description
γ-Thiobutyrolactone undergoes copolymerization with glycidyl phenyl ether to form poly(ester-alt-sulfide).
Application
γ-Thiobutyrolactone was used to terminate the ring opening polymerization of ω-pentadecalactone to synthesize difunctional polyesters. γ-Thiobutyrolactone was used to study the mechanism of metabolism of sulphur containing heterocyclic compounds by lignin-degrading basidiomycete Coriolus versicolor.
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Md Abdul Kafi et al.
Regenerative biomaterials, 7(2), 141-151 (2020-04-17)
Scaffold engineering has attracted significant attention for three-dimensional (3D) growth, proliferation and differentiation of stem cells in vitro. Currently available scaffolds suffer from issues such as poor ability for cell adhesion, migration and proliferation. This paper addresses these issues with
Jonathan Garel et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 12(15), 4144-4152 (2006-02-03)
Homocysteine thiolactone (tHcy) is deemed a risk factor for cardiovascular diseases and strokes, presumably because it acylates the side chain of protein lysine residues ("N-homocysteinylation"), thereby causing protein damage and autoimmune responses. We analysed the kinetics of hydrolysis and aminolysis
Tiny droplets make a big splash.
Michael Eisenstein
Nature methods, 3(2), 71-71 (2006-02-14)
D J Canney et al.
Bioorganic & medicinal chemistry, 6(1), 43-55 (1998-03-21)
Dihydro-2(3H)-furanones (gamma-butyrolactones) and dihydro-2(3H)-thiophenones (gamma-thiobutyrolactones) containing fluoroalkyl groups at positions C-3, C-4, and C-5 of the heterocyclic rings were prepared. The anticonvulsant/convulsant activities of the compounds were evaluated in mice. Brain concentrations of the compounds were determined and the effects
H Ichinose et al.
Applied microbiology and biotechnology, 58(4), 517-526 (2002-04-17)
The fungal conversions of sulfur-containing heterocyclic compounds were investigated using the lignin-degrading basidiomycete Coriolus versicolor. The fungus metabolized a series of sulfur compounds--25 structurally related thiophene derivatives--via several different pathways. Under primary metabolic conditions, C. versicolor utilized thiophenes, such as
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