101133
Butylmalonic acid
99%
Synonym(s):
1,1-Pentanedicarboxylic acid, 2-n -Butylmalonic acid, 2-Butylpropanedioic acid
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About This Item
Linear Formula:
CH3(CH2)3CH(CO2H)2
CAS Number:
Molecular Weight:
160.17
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
EC Number:
208-602-7
MDL number:
InChI key
MCRZWYDXIGCFKO-UHFFFAOYSA-N
InChI
1S/C7H12O4/c1-2-3-4-5(6(8)9)7(10)11/h5H,2-4H2,1H3,(H,8,9)(H,10,11)
SMILES string
CCCCC(C(O)=O)C(O)=O
assay
99%
form
solid
mp
105-107 °C (lit.)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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E Fransvea et al.
Archives of biochemistry and biophysics, 355(1), 93-100 (1998-07-02)
The impermeability of the inner membrane to protons is one of the four postulates of the chemiosmotic theory on the coupling mechanism between respiration and phosphorylation in mitochondria. However, oxygen uptake in isolated nonphosphorylating mitochondria requires that protons translocated from
H Breitbart et al.
Biochimica et biophysica acta, 1026(1), 57-63 (1990-07-09)
Calcium uptake into filipin-treated bovine spermatozoa is completely inhibited by the uncoupler CCCP or by ruthenium red. Both Pi and mitochondrial substrates are required to obtain the maximal rate of calcium uptake into the sperm mitochondria. Bicarbonate and other anions
R S Kaplan et al.
The Journal of biological chemistry, 260(18), 10293-10298 (1985-08-25)
The mitochondrial dicarboxylate carrier has been substantially purified from rat liver mitoplasts by extraction with Triton X-114 in the presence of cardiolipin followed by chromatography on hydroxylapatite. Upon incorporation of the hydroxylapatite eluate into phospholipid vesicles, an n-butylmalonate-sensitive malonate/malate exchange
P C Jocelyn et al.
Biochemical pharmacology, 31(22), 3645-3649 (1982-11-15)
Non-energy dependent transhydrogenase activity in submitochondrial particles is stimulated at pH 8 by some inhibitors of mitochondrial carboxylate translocases. On solubilising the enzyme or assaying it at pH 6 these inhibitors have little effect. Km values remain unchanged under all
R B Gregory et al.
Biochimica et biophysica acta, 1137(1), 34-38 (1992-10-06)
Isolated hepatocytes from hypothyroid, euthyroid and hyperthyroid rats have been employed to investigate the relative importance of reducing-equivalent shuttles for the transfer of hydrogen between cytoplasm and mitochondria during simultaneous ureogenesis and gluconeogenesis. In cells from hypothyroid animals, a 58%
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