100870
Bis(4-chlorophenyl)acetic acid
98%
Synonym(s):
4,4′-DDA
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About This Item
Linear Formula:
(ClC6H4)2CHCO2H
CAS Number:
Molecular Weight:
281.13
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
201-451-8
MDL number:
Assay:
98%
InChI key
YIOCIFXUGBYCJR-UHFFFAOYSA-N
InChI
1S/C14H10Cl2O2/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8,13H,(H,17,18)
SMILES string
OC(=O)C(c1ccc(Cl)cc1)c2ccc(Cl)cc2
assay
98%
mp
167-169 °C (lit.)
functional group
carboxylic acid, chloro
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Mitotane (1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane) metabolism in perfusion studies with dog adrenal glands.
J E Sinsheimer et al.
Drug metabolism and disposition: the biological fate of chemicals, 15(2), 267-269 (1987-03-01)
H van Dijk et al.
Methods and findings in experimental and clinical pharmacology, 8(3), 189-193 (1986-03-01)
A novel, sensitive system to determine immunological adjuvant activity is presented. It is based on the direct haemagglutinin response of mice to neuraminidase-treated sheep red blood cells (asialo-SRBC) seven days after i.p. immunization. For two model adjuvants it is shown
Development of an enzyme-linked immunosorbent assay for the quantification of DDA (2,2-bis(p-chlorophenyl) acetic acid) in urine.
B D Banerjee
Bulletin of environmental contamination and toxicology, 38(5), 798-804 (1987-05-01)
J Guilford et al.
Drug and chemical toxicology, 9(3-4), 239-252 (1986-01-01)
The possibility that lead could affect the metabolism of the insecticide 1,1-dichloro-2, 2-bis(p-chlorophenyl)ethane, DDD, was examined by studies of the effects of chronic oral Pb treatment on DDD conversion to 2,2-bis(p-chlorophenyl)acetic acid, DDA. Rats were given either distilled deionized water
Karsten Hemmrich et al.
Cytotherapy, 12(4), 547-553 (2010-04-08)
Obesity is correlated with chronic low-grade inflammation. Thus the induction of inflammation could be used to stimulate adipose tissue formation in tissue-engineering approaches. As nitric oxide (NO) is a key regulator of inflammation, we investigated the effect of NO and
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