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100013

4,4′-Dimethoxytrityl chloride

95%

Synonym(s):

DMT-Cl

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About This Item

Linear Formula:
C6H5C(C6H4OCH3)2Cl
CAS Number:
40615-36-9
Molecular Weight:
338.83
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
24846511
EC Number:
255-002-6
Beilstein/REAXYS Number:
2471942
MDL number:
MFCD00008409
Assay:
95%
Form:
solid
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Quality Level

200

assay

95%

form

solid

mp

119-123 °C (lit.)

functional group

chloro, phenyl

SMILES string

COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3

InChI

1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3

InChI key

JBWYRBLDOOOJEU-UHFFFAOYSA-N

General description

DMT-Cl is commonly used as a protecting group for various functional groups in organic synthesis.

Application

Hydroxyl protecting group for nucleosides and nucleotides.

signalword

Danger

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

8B - Non-combustible corrosive hazardous materials

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Journal of the American Chemical Society, 115, 4985-4985 (1993)
T Tuschl et al.
Biochemistry, 32(43), 11658-11668 (1993-11-02)
The three guanosines of the central core of a hammerhead ribozyme were replaced by 2-aminopurine ribonucleoside, xanthosine, isoguanosine, inosine, and deoxyguanosine. These analogues were incorporated by automated solid-phase synthesis, with the exception of isoguanosine. This was introduced by ligating a
Y Ueno et al.
Nucleic acids research, 21(19), 4451-4457 (1993-09-25)
The preparation of a nucleotidyl-peptide having a thymidine-5'-yl-(P-O)-serine phosphodiester bond, [H-Ala-Ser(pTpT)-Phe-OH](24) is described. After condensation between the phosphorylated peptide component and an oligonucleotide component, all protecting groups could be removed under neutral conditions without beta-elimination of the pTpT from the
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Global Trade Item Number

SKUGTIN
100013-5G04061833448410
100013-25G04061833544273