N0186
Nourseothricin sulfate
powder, suitable for cell culture, BioReagent
Synonym(s):
ClonNAT, NTC
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About This Item
UNSPSC Code:
12352207
NACRES:
NA.76
Product Name
Nourseothricin sulfate, suitable for cell culture
biological source
Streptomyces sp.
form
powder
storage temp.
2-8°C
Quality Level
Application
Nourseothricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.
Biochem/physiol Actions
Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.
General description
Chemical structure: peptidyl nucleoside, aminoglycoside antibiotic. Nourseothricin (NTC) is a mixture of the related compounds streptothricin C, D, E, and F.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
Packaging
10mg, 50mg
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
涉药品监管产品
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