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E6635

Ethylenediaminetetraacetic acid disodium salt dihydrate

Name: Ethylenediaminetetraacetic acid disodium salt dihydrate
Brand: SIGMA

Sigma Grade, suitable for plant cell culture, 98.5-101.5%

Synonym(s):

Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na₂, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na₂

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄N₂Na₂O₈ · 2H₂O

CAS Number:

6381-92-6

Molecular Weight:

372.24

Beilstein:

3900609

EC Number:

205-358-3

UNSPSC Code:

12352107

PubChem Substance ID:

24894632

NACRES:

NA.77

grade

Sigma Grade

Quality Level

200

Assay

98.5-101.5%

form

powder

reaction suitability

reagent type: chelator

technique(s)

cell culture | plant: suitable

mp

248 °C (dec.) (lit.)

solubility

H₂O: soluble, clear, colorless

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

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Related Categories

Chelating & Reducing Agents for Research

Plant Culture Media

General description

Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions, especially with cations to form an octahedral complex. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Application

Ethylenediaminetetraacetic acid disodium salt dihydrate has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten. It has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Pictograms

GHS08,GHS07

Signal Word

Warning

Hazard Statements

H332,H373

Precautionary Statements

P260 - P271 - P304 + P340 + P312 - P314 - P501

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

Target Organs

Respiratory Tract

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Isolation of Intact Vacuoles from Petunia Petals and Extraction of Sequestered Glycosylated Phenylpropanoid Compounds

Skaliter O, et al.

Bio-protocol, 8(13), 56-56 (2017)

A Phosphopeptide Purification Protocol for the Moss Physcomitrella paten

Wang, X and He Y

Bio-protocol, 5(14), 56-56 (2015)

Induced Plant Accumulation of Lithium

Kavanagh L, et al.

Geostandards Newsletter, 8(2), 56-56 (2018)

EDTA chelation therapy for cardiovascular disease: a systematic review

Seely DMR, et al.

BMC Cardiovascular Disorders, 5(1), 32-32 (2005)

Environmental fate and microbial degradation of aminopolycarboxylic acids

Bucheli-Witschel M and Egli T

FEMS Microbiology Reviews, 25(1), 69-106 (2001)

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