推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
human, mouse, rat
技术
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... AFP(174)
一般描述
基因AFP（α胎蛋白）编码一种分子量为70kDa的血浆糖蛋白。该基因定位于人类4号染色体。该基因与血清白蛋白在进化上相关，血清白蛋白也定位于人类4号染色体。在胚胎卵黄囊和肝脏发育过程中，它是与血清白蛋白一起合成的。
免疫原
AFP抗体通过靶向人AFP氨基末端附近的14个氨基酸多肽获得。
应用
兔抗-AFP抗体可用于免疫荧光。
生化/生理作用
αAFP基因编码的-胎蛋白可参与到胎儿和增生的成人肝细胞中脂肪酸的调节。在急性肝损伤中发现其表达有所提高，表明活跃的肝再生。它与脂肪肝疾病（FLD）相关，而这是一种可能导致肝硬化和肝细胞癌的疾病。它可作为HCC（肝细胞癌）的一种肿瘤标志物。
特点和优势
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
联系
可以使用阻断肽SBP3500533阻断该抗体的作用。
外形
以含有0.02%叠氮化钠的PBS形式提供。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
W Samuel Fagg et al.
Cell transplantation, 30, 963689721993780-963689721993780 (2021-03-05)
Stem cell transplantation to the liver is a promising therapeutic strategy for a variety of disorders. Hepatocyte transplantation has short-term efficacy but can be problematic due to portal hypertension, inflammation, and sinusoidal thrombosis. We have previously transplanted small mouse endoderm
Wenwen Deng et al.
Journal of agricultural and food chemistry, 64(6), 1264-1273 (2016-01-27)
Pleurotus eryngii is a medicinal/edible mushroom with great nutritional value and bioactivity. Its polysaccharide has recently been developed into an effective gene vector via cationic modification. In the present study, cationized P. eryngii polysaccharide (CPS), hybridized with calcium phosphate (CP)
M E Harper et al.
American journal of human genetics, 35(4), 565-572 (1983-07-01)
Albumin and alpha-fetoprotein are structurally related serum proteins, having a similar gene structure and, conceivably, a common evolutionary origin. To test their relative arrangement in the human genome, the serum albumin and alpha-fetoprotein genes were mapped by in situ hybridization
Surachate Siripongsakun et al.
Journal of gastroenterology and hepatology, 29(1), 157-164 (2013-12-21)
The performance of alpha-fetoprotein (AFP) in the detection of hepatocellular carcinoma (HCC) recurrence after radiofrequency ablation was analyzed. One hundred and forty-six solitary HCC lesions treated by radiofrequency ablation were evaluated. Using the AFP cutoff level at ≥ 20 ng/mL, tumors were
Association between serum alpha-fetoprotein levels and fatty liver disease: a cross-sectional study.
Ping Xu et al.
World journal of gastroenterology, 20(33), 11865-11870 (2014-09-11)
To investigate the association between serum alpha-fetoprotein (AFP) levels and fatty liver disease (FLD) in a Chinese population. A cross-sectional study was performed among subjects who presented for a health examination at the First Affiliated Hospital, College of Medicine, Zhejiang
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