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Merck
CN
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文件

安全信息

HPA001906

Sigma-Aldrich

抗ATRX 兔抗

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

别名:

ATP依赖性解旋酶ATRX抗体, ATRX抗体 - 兔抗ATRX抗体, Atrx抗体, X连锁解旋酶II抗体, Znf-HX抗体, JMS, RAD54, XH2, XNP

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所有图片(7)

About This Item

UNSPSC代码:
12352203
人类蛋白质图谱编号:
HPA001906
NACRES:
NA.41

生物来源

rabbit

质量水平

100

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

产品线

Prestige Antibodies® Powered by Atlas Antibodies

形式

buffered aqueous glycerol solution

种属反应性

human

增强验证

orthogonal RNAseq
RNAi knockdown
Learn more about Antibody Enhanced Validation

技术

immunoblotting: 0.04-0.4 μg/mL
immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:500-1:1000

UniProt登记号

P46100

应用

research pathology

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ATRX(546)

相关类别

免疫原

对应于α地中海贫血/智力低下综合征X连锁的重组蛋白。

序列
AAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRR

应用

由Atlas Antibodies提供技术支持的所有Prestige Antibodies抗体均由人类蛋白质图集(HPA)项目开发和验证，因此受到业内最广泛的表征支持。

人类蛋白质图集项目可以分为三大部分：人体组织图谱、癌症图谱和人类细胞图谱。在组织和癌症图谱项目支持下产生的抗体已通过对数百种正常和疾病组织的免疫组织化学分析得到了验证，并且通过近期人类细胞图谱项目的努力，许多抗体已经过免疫荧光分析的表征，从而绘制人类蛋白质组图谱，不仅是在组织水平上，现在已经达到亚细胞水平。在人类蛋白质图集项目网站上单击图像库链接，可以查看这些图像和庞大的数据集。我们提供Prestige Antibodies®抗体的实验方案和其他有用信息。兔抗-ATRX抗体可用于免疫组化实验。

特点和优势

Prestige Antibodies®是经过高度表征和广泛验证的抗体，同时还有一个优点是其每个靶标的所有可用表征数据都可以通过位于此页面顶部产品名称下方的人类蛋白质图谱门户进行访问。Prestige Antibodies®对其他蛋白质的独特性和低交叉反应性是通过严密的抗原区域选择、亲和纯化和严格的选择来实现的。针对每一个Prestige Antibody都存在有对应的Prestige抗原对照，并可在链接区域内找到。

每个Prestige Antibody均按照以下方法进行测试：
  • 44例正常人类组织以及20例最常见癌症类型组织的IHC组织阵列。
  • 364个人类重组蛋白片段的蛋白阵列。

联系

相应抗原APREST74299

外形

溶于磷酸盐缓冲盐水，pH 7.2，含有40%甘油和0.02%叠氮化钠

法律信息

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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WGK

WGK 1

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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Katharina I Deeg et al.
Frontiers in oncology, 6, 186-186 (2016-09-08)
Telomere maintenance is a hallmark of cancer as it provides cancer cells with cellular immortality. A significant fraction of tumors uses the alternative lengthening of telomeres (ALT) pathway to elongate their telomeres and to gain an unlimited proliferation potential. Since
J Gregory Cairncross et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 32(8), 783-790 (2014-02-12)
Patients with 1p/19q codeleted anaplastic oligodendroglial tumors who participated in RTOG (Radiation Therapy Oncology Group) 9402 lived much longer after chemoradiotherapy (CRT) than radiation therapy (RT) alone. However, some patients with noncodeleted tumors also benefited from CRT; survival curves separated
Yavuz Oktay et al.
Scientific reports, 6, 27569-27569 (2016-06-11)
The single nucleotide polymorphism rs55705857, located in a non-coding but evolutionarily conserved region at 8q24.21, is strongly associated with IDH-mutant glioma development and was suggested to be a causal variant. However, the molecular mechanism underlying this association has remained unknown.
Gerald F Reis et al.
Journal of neuropathology and experimental neurology, 74(5), 442-452 (2015-04-09)
Lower-grade (World Health Organization Grades II and III) gliomas vary widely in clinical behavior and are classified as astrocytic, oligodendroglial, or mixed. Anaplasia depends greatly on mitotic activity, with CDKN2A loss considered as the most common mechanism for cell cycle
Brooke E Howitt et al.
The Journal of pathology, 235(1), 37-49 (2014-09-19)
Müllerian adenosarcoma (MA) is a rare mixed mesenchymal tumour of the female genital tract, composed of malignant stroma and benign-appearing epithelium. Sarcomatous overgrowth (SO) is the only established histological variable associated with higher stage and shorter survival. Specific molecular or
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