所有图片(1)
别名:
(S)-BAY-678, 2-Pyridinecarbonitrile, 5-[(4S)-5-acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-, 5-{(4S)-5-Acetyl-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidin-4-yl}pyridine-2-carbonitrile
经验公式（希尔记法）:
C20H15F3N4O2
检测方案
≥98% (HPLC)
形式
powder
旋光性
[α]/D -21 to -29°, c = 0.5 in methanol
颜色
white to light brown
溶解性
DMSO: 20 mg/mL, clear
储存温度
2-8°C
SMILES字符串
CC(N1C2=CC=CC(C(F)(F)F)=C2)=C(C(C)=O)[C@H](C3=CN=C(C#N)C=C3)NC1=O
InChI
1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21,22)23/h3-8,10,18H,1-2H3,(H,26,29)/t18-/m0/s1
InChI key
PGIVGIFOWOVINL-SFHVURJKSA-N
生化/生理作用
BAY-677 is the negative control probe for BAY-678, which is a human neutrophil elastase (HNE) inhibitor with >2,000-fold selectivity for HNE over a panel of 21 other serine proteases. For characterization details of BAY-678 and BAY-677, please visit the BAY-677 probe summary on the Structural Genomics Consortium (SGC) website.
BAY-678, the active HNE probe, is available from Sigma. To learn more about and purchase BAY-678, click here.
To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc
BAY-678, the active HNE probe, is available from Sigma. To learn more about and purchase BAY-678, click here.
To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc
特点和优势
BAY-677 is a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门