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H8000

Sigma-Aldrich

L-Histidine

≥99% (TLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773

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About This Item

Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
71-00-1
Molecular Weight:
155.15
Beilstein:
84088
EC Number:
200-745-3
MDL number:
MFCD00064315
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24895816
NACRES:
NA.26

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Product Name

L-Histidine, ReagentPlus®, ≥99% (TLC)

Quality Level

200

product line

ReagentPlus®

Assay

≥99% (TLC)

form

powder

color

white to off-white

mp

282 °C (dec.) (lit.)

solubility

0.5 M HCl: 50 mg/mL

application(s)

cell analysis

SMILES string

N[C@@H](Cc1c[nH]cn1)C(O)=O

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1 of 4

This Item
E045E030E037
乙醇-50标准液 CRM 50 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®

E029

乙醇-50标准液 CRM

乙醇-40 40 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®

E045

乙醇-40

乙醇-80 标准液 CRM 80 mg/dL in H2O, ampule of 10 × 1.2 mL, certified reference material, Cerilliant®

E030

乙醇-80 标准液 CRM

乙醇-80 80 mg/dL in H2O, ampule of 5 × 5 mL, certified reference material, Cerilliant®

E037

乙醇-80

format

single component solution

format

single component solution

format

single component solution

format

single component solution

form

liquid

form

liquid

form

liquid

form

liquid

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

-

grade

certified reference material

grade

certified reference material

grade

certified reference material

grade

certified reference material

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Application

L-histidine has been used for the selection of transformed cells.[1] It has also been used to study its effects on the formation of verteporfin cross-linked oligomers in cellular homogenates.[2]

Biochem/physiol Actions

L-Histidine is an essential amino acid.[3] It binds to metal ions and may aid in the transport of copper.[4] Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.[5]
Precursor of histamine by action of histidine decarboxylase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000438956
    0000438949
    0000438949
    0000438956
    0000433968

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    Catherine Collin, Masaru Minami, Hasan Parvez, Hideya Saito, Simone Parvez, Qureshi, Claude Reiss
    Advances in Neurochemistry (2005)
    Roger L. Lundblad
    Chemical Reagents for Protein Modification (2014)
    Kakulavarapu V Rama Rao et al.
    The American journal of pathology, 176(3), 1400-1408 (2010-01-16)
    Brain edema and the associated increase in intracranial pressure are potentially lethal complications of acute liver failure (ALF). Astrocyte swelling (cytotoxic edema) represents a significant component of the brain edema in ALF, and elevated blood and brain ammonia levels have
    Verteporfin-induced formation of protein cross-linked oligomers and high molecular weight complexes is mediated by light and leads to cell toxicity
    Eleni K
    Scientific Reports (2017)
    Markerless Gene Editing in the Hyperthermophilic Archaeon Thermococcus kodakarensis
    Alexandra m
    Bio-protocol (2017)
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