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HLPPMAG-57K

MILLIPLEX® Human Liver Protein Panel

Configurable Human Liver Protein 9-plex Panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000

Key Documents

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Product Name

MILLIPLEX® Human Liver Protein Panel, Configurable Human Liver Protein 9-plex Panel

species reactivity

human

Quality Level

200

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 100.2%
(HGF)
accuracy: 93.7%
(ANGPTL3)
accuracy: 94.2%
(AFP)
accuracy: 96.6%
(FGF-23)
accuracy: 96.8%
(ANGPTL4)
accuracy: 98.8%
(FGF-21)
sensitivity: 0.004 ng/mL
(MinDC+2SD; FGF-21)
sensitivity: 0.014 ng/mL
(MinDC+2SD; FGF-23)
sensitivity: 0.018 ng/mL
(MinDC+2SD; HGF)
sensitivity: 0.054 ng/mL
(MinDC+2SD; FGF-19)
sensitivity: 0.144 ng/mL
(MinDC+2SD; AFP)
sensitivity: 0.218 ng/mL
(MinDC+2SD; FABP1)
sensitivity: 0.725 ng/mL
(MinDC+2SD; ANGPTL3)
sensitivity: 0.847 ng/mL
(MinDC+2SD; ANGPTL6)
sensitivity: 2.150 ng/mL
(MinDC+2SD; ANGPTL4)
standard curve range: 0.01-10 ng/mL
(FGF-21)
standard curve range: 0.04-30 ng/mL
(FGF-23)
standard curve range: 0.07-50 ng/mL
(HGF)
standard curve range: 0.14-100 ng/mL
(AFP)
standard curve range: 0.14-100 ng/mL
(FGF-19)
standard curve range: 0.27-200 ng/mL
(FABP1)
standard curve range: 0.69-500 ng/mL
(ANGPTL3)
standard curve range: 1.37-1000 ng/mL
(ANGPTL6/AGF)
standard curve range: 5.49-4000 ng/mL
(ANGPTL4)
inter-assay cv: <20%
intra-assay cv: <10%
(AFP)
inter-assay cv: <20%
intra-assay cv: <10%
(ANGPTL3)
inter-assay cv: <20%
intra-assay cv: <10%
(ANGPTL4)
inter-assay cv: <20%
intra-assay cv: <10%
(ANGPTL6/AGF)
inter-assay cv: <20%
intra-assay cv: <10%
(FABP1)
inter-assay cv: <20%
intra-assay cv: <10%
(FGF-19)
inter-assay cv: <20%
intra-assay cv: <10%
(FGF-21)
inter-assay cv: <20%
intra-assay cv: <10%
(FGF-23)
inter-assay cv: <20%
intra-assay cv: <10%
(HGF)

technique(s)

multiplexing: suitable

input

serum

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

General description

IL-1β, IL-6, IL-8, IL-10, TNFα, IFNγ, and IL-12p70 are key cytokines involved in inflammation, immune regulation, and host defense. These analytes help characterize pro- and anti-inflammatory responses, making them essential for studying immune activation, infection, autoimmune diseases, and immunotoxicity. Their combined measurement enables comprehensive profiling of human inflammatory and immune pathways.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance Simultaneously analyze up to 9 analytes in human serum or plasma samples.Analytes included: α-Fetoprotein (AFP), ANGPTL3, ANGPTL4, ANGPTL6, FABP1, FGF-19, FGF-21, FGF-23, and Hepatocyte Growth Factor (HGF)Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:• Multiplex detection of 9 liver-secreted proteins in one assay• Magnetic bead-based Luminex® xMAP® technology• Compatible with serum, plasma, and cell/tissue culture samples• Designed for metabolic and liver disease research• High-throughput and customizable formatBenefits:• Efficient and cost-effective biomarker analysis• Minimal sample volume required• Enables comprehensive liver profiling• Supports biomarker discovery and translational research• Delivers reliable, reproducible results

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

新产品
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Manjunath Ramanjaneya et al.
Frontiers in endocrinology, 11, 568500-568500 (2020-10-27)
Background: The fibroblast growth factors (FGF) 19 subfamily, also referred to as endocrine FGFs, includes FGF19, FGF21, and FGF23 are metabolic hormones involved in the regulation of glucose and lipid metabolism. Fetuin-A is a hepatokine involved in the regulation of
Stefano Bartesaghi et al.
Molecular therapy. Nucleic acids, 28, 500-513 (2022-05-21)
Fibroblast growth factor 21 (FGF21) is a promising therapeutic agent for treatment of type 2 diabetes (T2D) and non-alcoholic steatohepatitis (NASH). We show that therapeutic levels of FGF21 were achieved following subcutaneous (s.c.) administration of mRNA encoding human FGF21 proteins.
Imad Tarhoni et al.
Journal of immunoassay & immunochemistry, 39(1), 84-98 (2018-01-09)
Angiogenesis is associated with tumor progression in a range of malignancies. Herein, we develop custom immunobead assays for several mechanistically important targets and evaluated these against sera from cohorts of non-small cell lung cancer (NSCLC) patients. Antigen "capture" antibodies for
Nigel Davies et al.
Molecular therapy. Nucleic acids, 24, 369-384 (2021-04-20)
Lipid nanoparticles (LNPs) are the most clinically advanced delivery system for RNA-based drugs but have predominantly been investigated for intravenous and intramuscular administration. Subcutaneous administration opens the possibility of patient self-administration and hence long-term chronic treatment that could enable messenger

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Quality Control Range Sheet- HLPP-114 and HLPP-214
Protocol- HLPPMAG-57K
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