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Merck
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HCVD3MAG-67K

MILLIPLEX® 人心血管疾病（急性期）磁珠板3 - 心血管疾病多重检测

Configurable Human CVD (Acute Phase) 10-Plex Panel 3

别名:

human CVD APP immunoassay panel, luminex human cardiovascular disease acute phase proteins multiplex assay, millipore human CVD acute phase proteins multiplex kit, CVD assay snapshot, CVD detection kit, CVD multiplex product sheet, cardiovascular biomarker listing, cardiovascular biomarker profile, human CVD assay overview, human cardiovascular panel summary, human inflammation product info, human vascular health research tool, vascular inflammation biomarker panel

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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species reactivity

human

Quality Level

200

assay range

accuracy: 102%
(Haptoglobin), accuracy: 109%
(AGP), accuracy: 113%
(Platelet Factor-4), accuracy: 117%
(Adipsin), standard curve range: 0.004-15 ng/mL
(L-Selectin & SAP), standard curve range: 0.012-50 ng/mL
(CRP), standard curve range: 0.037-150 ng/mL
(PF4), standard curve range: 0.061-250 ng/mL
(HPTGN), standard curve range: 0.098-400 ng/mL
(AGP & Adipsin), standard curve range: 0.244-1,000 ng/mL
(Fetuin A & vWF), standard curve range: 0.488-2,000 ng/mL
(A2M)

technique(s)

multiplexing: suitable

input

serum plasma (Cell culture, cell culture supernatants)

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

相关类别

General description

Cardiovascular disease is driven by a complex interplay of inflammation, coagulation, lipid metabolism, and immune response. This set of biomarkers—α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin, Adipsin/Factor D, CRP, Fetuin A, Fibrinogen, Haptoglobin, sL-Selectin, Platelet Factor 4 (PF4)/CXCL4, and Serum Amyloid P (SAP)—captures key physiological processes associated with cardiovascular risk and progression. These analytes are involved in acute-phase response, vascular inflammation, platelet activation, and metabolic regulation, making them highly relevant for research in atherosclerosis, thrombosis, and systemic inflammation.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 10 analytes in human serum, plasma, or cell culture supernatants.

Analytes included: α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin, Adipsin/Factor D, CRP, Fetuin A, Fibrinogen, Haptoglobin, sL-Selectin, Platelet Factor 4 (PF4)/CXCL4, Serum Amyloid P (SAP)

Note: Fibrinogen cannot be measured in serum samples.Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

通过在此面板中选择可用的分析物来设计多重试剂盒。

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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Rima Habre et al.
Environment international, 118, 48-59 (2018-05-26)
Exposure to ultrafine particles (UFP, particles with aerodynamic diameter < 100 nm) is associated with reduced lung function and airway inflammation in individuals with asthma. Recently, elevated UFP number concentrations (PN) from aircraft landing and takeoff activity were identified downwind of the Los
Daniel O'Connor et al.
Molecular systems biology, 16(11), e9888-e9888 (2020-11-20)
Neisseria meningitidis is a major cause of meningitis and septicaemia. A MenB vaccine (4CMenB) was licensed by the European Medicines Agency in January 2013. Here we describe the blood transcriptome and proteome following infant immunisations with or without concomitant 4CMenB
Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes.
Woodson, SE; Freiberg, AN; Holbrook, MR
Virus Research null
Yaochen Zhang et al.
PloS one, 12(7), e0182141-e0182141 (2017-07-28)
Fibrinogen, 1 of 13 coagulation factors responsible for normal blood clotting, is synthesized by hepatocytes. Detailed roles of the orphan nuclear receptors regulating fibrinogen gene expression have not yet been fully elucidated. Here, we identified estrogen-related receptor gamma (ERRγ) as
Anna C Belkina et al.
Frontiers in immunology, 9, 2783-2783 (2018-12-21)
Even with effective viral control, HIV-infected individuals are at a higher risk for morbidities associated with older age than the general population, and these serious non-AIDS events (SNAEs) track with plasma inflammatory and coagulation markers. The cell subsets driving inflammation
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